A Critical Review and Local Audit of the Prevalence of Mental Ill-Health in Heart Failure Patients

Heart Failure and mental ill-health


Introduction: A systematic review and meta-analysis of randomised controlled trials examining coronary heart disease and depression comorbidity. The number of useable randomised controlled trials (RCT) that specifically assess heart failure and depression is limited.

Aim: To establish if depression results in poor adherence to therapy in patients with coronary heart disease. To review the available data and explore the current interventions employed to improve coronary heart disease prognosis with depression comorbidity. To systematically review the efficacy of multidisciplinary shared care for depression in adults who have heart disease.

Method: This concept scoping study was conducted in two phases; the first was a systematic review of the literature and the second part was local data analysis. Statistical analysis was performed using RevMan® V.5.3 (Cochrane Community).

Findings: Patient who received multidisciplinary collaborative care showed significantly reduced major adverse cardiac outcomes in patients with cardiovascular diseases. They also demonstrated higher rates of self-reported remission of depression. The review also showed end point mortality after PCI was associated with patients having depression. Local population data showed that 26% of heart failure patients had mental ill health comorbidity, however only 12% had a formal diagnosis recorded.

Conclusion: Depression is associated with poor cardiac outcomes in patients with coronary artery disease. It is widespread in patients with cardiovascular disease and must be screened for throughout the management plan.

Keywords: Independent prescribing pharmacist, Heart Failure, Depression, Anxiety, Primary Health Care, General Practice


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Ahmed, M., hana morrissey, and P. Ball. “A Critical Review and Local Audit of the Prevalence of Mental Ill-Health in Heart Failure Patients”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 12, no. 5, Mar. 2020, https://innovareacademics.in/journals/index.php/ijpps/article/view/37159.
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