POTENCY OF Γ-ORYZANOL-RICH BLACK RICE BRAN (ORYZA SATIVA L. INDICA) EXTRACT FOR TYROSINASE INHIBITION
Keywords:Black rice bran, Gamma oryzanol, Tyrosinase inhibitor, Lightening agent
Objective: The objectives of this study were to quantify γ-oryzanol in an ethanolic extract of Oryza sativa L. Indica (black rice) bran and to evaluate its activity as a tyrosinase inhibitor.
Methods: Black rice bran was extracted via maceration in 96% ethanol, and the γ-oryzanol concentration in the extract was measured through high-performance liquid chromatography. The applicability of the extract as a skin lightening agent was determined by evaluating its tyrosinase inhibition activity.
Results: The dry rice bran contained 118.572 mg/g of γ-oryzanol, and the extract inhibited tyrosinase activity at an IC50 of 74.8%.
Conclusion: The black rice bran extract was sufficiently potent for use in skin lightening formulations.
Zion Market Research. Global skin lightening products market is expected to reach Around USD 8,895 million by 2024. Available from: https://www.zionmarketresearch.com/news/skin-lightening-products-market. [Last accessed 10 Apr 2019]
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