ASSESSMENT OF ANTIBIOTIC USAGE PATTERN IN PATIENTS OF PEDIATRIC DEPARTMENT-A PROSPECTIVE STUDY
Objective: The study aimed to assess the antibiotic usage pattern in patients of the pediatric department in ESI Hospital, Indiranagar, Bangalore.
Methods: A prospective six-month observational study was conducted in the pediatric department. The history of the patients was collected from the case sheets and the patient demographic details were also collected. The details of antibiotics prescribed and the other therapy applied to the patients were collected in terms of dosage, duration, and route of administration. The antibiotic consumption was assessed based on qualitative and quantitative indicators which assess the appropriateness of antibiotic use, and the dosage of antibiotics prescribed, respectively. Regarding the qualitative evaluation of antibiotic consumption, the World Health Organization (WHO) guideline was considered to appraise compliance with indication and dosing.
Results: Distribution of drug prescription indicators showed that the average number of drugs per encounter was 3.7, which is more than the standards suggested by WHO and should be reduced as much as possible to mitigate polypharmacy and its consequences. 93.45% of encounters existed leastwise with one or more antibiotics, which was higher than the WHO standards. Almost 56.08% of drugs were prescribed considering their generic name, which was very much lower than the ideal percentage recommended by WHO.
Conclusion: The percentage of encounters with one or more antibiotics was very higher than the WHO standard percentage, which indicates the irrationality of antibiotic prescribing. To minimize the irrationality of prescriptions and their inappropriateness, effective interventions and compliance with antibiotic prescribing guidelines are required.
2. Wei TI, Ascobat P, Rohsiswatmo R, Instiaty I. Qualitative review of antibiotic use for neonatal sepsis. Int J Appl Pharm 2018;10:364-6.
3. PC TS MS, Mohan Reddy M, CG Rao MM. Assessment of public knowledge and attitude regarding antibiotic use in a tertiary care hospital. Asian J Pharm Clin Res 2016;9:118-22.
4. Leekha S, Terrell CL, Edson RS. General principles of antimicrobial therapy. Mayo Clin Proc 2011;86:156–67.
5. M Dickerson Lori, Mainous Arch, Carek Peter. The pharmacist's role in promoting optimal antimicrobial use pharmacotherapy. J Am Coll Clin Pharm 2000;20:711-23.
6. Shanmugapriya S, Saravanan T, Rajee SS, Venkatrajan R, Thomas PM. Drug prescription pattern of outpatients in a tertiary care teaching hospital in Tamil Nadu. Perspect Clin Res 2018;9:133-8.
7. Nasution ES, Muchtar R. Evaluation of antibiotics utilization on pediatric outpatients in Universitas Sumatera Utara hospital, Medan. Asian J Pharm Clin Res 2018;11:427-9.
8. Van Houten MA, Luinge K, Laseur M, Kimpen JL. Antibiotic utilization for hospitalized pediatric patients. Int J Antimicrob Agents 1998;8:161-4.
9. Sharma S, Bowman C, Alladin Karan B, Singh N. Antibiotic prescribing patterns in the pediatric emergency department at georgetown public hospital corporation: a retrospective chart review. BMC Infect Dis 2016;19:160-70.
10. Khaled MA, Asif Ansari SM. Prescribing pattern of antibiotics in pediatric patients in the Jazan region, Kingdom of Saudi Arabia. RGUHS J Pharm Sci 2014;4:120-4.
11. Sharma K, Raszynski A, Totapally BR. The impact of body mass index on resource utilization and outcomes of children admitted to a pediatric intensive care unit. SAGE Open Med 2019;7:300-7.
12. Pradeepkumar B, Alameri T, Narayana G, Reddy YP, Ramaiah JD. Assessment of antibiotic prescribing pattern in pediatric patients: a cross-sectional hospital-based survey. CHRISMED J Health Res 2017;4:235-7.
13. Gopal MB, Thiyagarajan P, Venugopal V, Kumar VN. A study on antibiotic prescription among hospitalized pediatric patients at a referral center in Puducherry, India. Int J Contemp Pediatr 2017;4:700-5.
14. Ahmed AM, Awad AI. Drug use practices at pediatric Hospitals of Khartoum State, Sudan. Ann Pharmacother 2010;44:86-93.
15. Fadare J, Olatunya O, Oluwayemi O, Ogundare O. Drug prescribing pattern for under-fives in a pediatric clinic in South-Western Nigeria. Ethiop J Health Sci 2015;25:73-8.
16. Shatavisa Mukherjee, Sukanta Sen, Nikhil Era, Arunava Biswas, Kalpana Datta, Santanu K Tripathi. Antibiotic usage pattern among inpatients of a pediatric ward in a tertiary care hospital in Eastern India. Int J Res Med Sci 2017;3:3681-6.
17. Pise HN, Padwal SL, Jadhav RR, Deshmukh VS, Jadhav AD, Kolhe AM. Drug prescribing and dispensing pattern in pediatrics outpatient clinic of a rural tertiary-care teaching hospital. Natl J Physiol Pharm Pharmacol 2015;5:313-7.
This work is licensed under a Creative Commons Attribution 4.0 International License.