• NAZHA SAMRI Univesity Chouaib Doukklai
  • LAILA HSAINE Marine Biotechnology and the Environment Laboratory (BIOMARE) Faculty of Science, University Chouaib Doukkali- El Jadida-Morocco
  • SOUKAINA ELKAFHI Marine Biotechnology and the Environment Laboratory (BIOMARE) Faculty of Science, University Chouaib Doukkali- El Jadida-Morocco
  • SAMIRA KHLIFI Marine Biotechnology and the Environment Laboratory (BIOMARE) Faculty of Science, University Chouaib Doukkali- El Jadida-Morocco
  • SAMIRA ETAHIRI Marine Biotechnology and the Environment Laboratory (BIOMARE) Faculty of Science, University Chouaib Doukkali- El Jadida-Morocco


Objective : Marine algae are considered to be one of the largest sources for biogenic compounds. They produce a wide variety of chemically active metabolites that possess antibacterial, antifungal properties how are also finding importance in therapeutics. The aim of this study was to evaluate the antibacterial activity of seven brown marine algae against three Gram-positive bacteria (Staphylococcus epidermidis, Staphylococcus aureus and Streptococcus pyogenes), and three Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia).

Methods : Antifungal activity was evaluated against two fungi (Aspergillus Niger and Candidas tropicalis). For these, 35 algal extracts were prepared with five organic solvents methanol/water, methanol, dichloromethane/methanol, dichloromethane and ethyl acetate.

Results : Of all algal extracts tested, the methanol/water extract of Cystoseira tamariscifolia, showed maximum antibacterial activity against Staphylococcus aureus (MIC=2 µg/ml). Concerning antifungal activity, the lowest MIC value (5 µg/ml) was shown in the methanol/water extract of laminaria ochroleuca against Candida tropicalis and in the dichloromethanolic extract of Sargassum vulgare against Aspergillus niger.

Conclusion : These Results indicate that these algal extracts can further be analyzed and purified for relevant antibacterial and antifungal compounds which can be used in therapeutics and other applications.


Keywords: Brown algae, antibacterial activity, antifungal activity, solvent extracts.


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