A NEW ALKALOID FROM DERRIS INDICA (LAM) BENNETT SEED OIL: ISOLATION AND CHARACTERIZATION
Objective: The aim of the study was to isolate alkaloid compound from seed oil of Derris indica (Lam) Bennett where relevant antimicrobial properties in traditional medicines.
Methods: The plant was selected based on their usage in traditional medicines and ethnopharmacological importance. Crude extract from D. indica seeds fractioned with different solvents through column chromatography. Isolated pure fraction was identified and characterized using UV, FTIR, 1HNMR and Mass spectroscopy.
Results: D. indica seeds hexane extract on fractionation with ethyl acetate and methanol through column chromatography yielded a crystalline fraction. The fraction was identified as alkaloid group and characterized as a 2-(6-methoxyphenanthridin-8-yl) propan-2-ol. The compound is a new report from D. indica seed oil.
Conclusion: The usage of D. indica plant is much in traditional health care for treatment of diseases. Isolation of alkaloid compound from D. indica seeds in traditional herbal medicines may be found a good source of drug discovery.
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