A STUDY OF VANCOMYCIN RESISTANT ENTEROCOCCI ISOLATED FROM URINARY TRACT INFECTIONS


Wavare Sanjay M, Ghorpade Mv, Gajul Shivali V, Sajjan Annapurna G, Karigoudar Rashmi M

Abstract


Objective: Vancomycin resistant enterococci (VRE) are becoming a major emergence problem concern in urinary tract infection (UTI). This study provides accurate and complete description of antimicrobial susceptibility pattern and to know the prevalence of VRE in this area.

Methods: A total of 3400 urine samples were collected and processed bacteriologically. The enterococci was isolated and identified by biochemical tests and Vitek 2. VRE was determined by disc diffusion, agar dilution and Vitek 2 automated machine. Statistical analysis was done by Graph Pad InStat Software.

Results: The 143 (4.2%) enterococci were isolated from UTI patients. The incidence was higher in young females and old males. E. faecalis (78%) is the most common isolate followed by E. faecium (15%). The rare species (9%) like E. durans, E. avium, E. gallinarum and E. hirae were also isolated. Fosfomycin (96.5%) and nitrofurantoin (93%) was the drug of choice for enterococcal UTI while linezolid (98.6%) also can be used to treat other enterococcal infections. Among the UTI 98.6% enterococci were susceptible to vancomycin.

Conclusion: Empirical therapy for enterococcal infections should be guided by local patterns of drug resistance. Linezolid, fosfomycin or nitrofurantoin may be considered to treat the patients with VRE.

 


Keywords


Enterococci, Urinary Tract Infection, Vancomycin Resistance

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About this article

Title

A STUDY OF VANCOMYCIN RESISTANT ENTEROCOCCI ISOLATED FROM URINARY TRACT INFECTIONS

Keywords

Enterococci, Urinary Tract Infection, Vancomycin Resistance

Date

01-04-2015

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Issue 5, 2015 Page: 337-339

Online ISSN

0975-1491

Statistics

255 Views | 53 Downloads

Authors & Affiliations

Wavare Sanjay M
Department of Medical Microbiology BLDEU's Shri. B.M. Patil Medical College, Vijapur
India

Ghorpade Mv
Registrar Krishna Institute of Medical Sciences University
India

Gajul Shivali V
Registrar Krishna Institute of Medical Sciences University
India

Sajjan Annapurna G
Registrar Krishna Institute of Medical Sciences University
India

Karigoudar Rashmi M
Registrar Krishna Institute of Medical Sciences University
India


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