ANTI INFLAMMATORY ACTIVITY OF ERYTHRINA VARIEGATA


V. R. Krishna Raju Mantena, G. Tejaswini

Abstract


Objective: Erythrina variegata had been widely used for its reported biological activity in indigenous system of medicine. The present investigation was carried out to find the anti-inflammatory effect of ethanolic extract of Erythrina variegata in albino rats.

Methods: The anti-inflammatory activity was evaluated using acute inflammatory model like carrageenan induced paw edema and chronic inflammatory model like cotton pellet induced granuloma respectively.

Results: The ethanolic extract in different doses (200, and 400mg/kg, p. o) exhibited dose dependent and significant antiinflammatory activity in acute and chronic model of inflammation.

Conclusion: The alcoholic extract of Erythrina variegata has anti-inflammatory activity. This activity was related to the dose and these results corroborate the potential traditional use of the plant in folk medicine.


Keywords


Erythrina variegata, Anti-inflammatory, Carrageenan induced paw edema, Cotton pellet granuloma

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About this article

Title

ANTI INFLAMMATORY ACTIVITY OF ERYTHRINA VARIEGATA

Keywords

Erythrina variegata, Anti-inflammatory, Carrageenan induced paw edema, Cotton pellet granuloma

Date

01-04-2015

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Issue 4, 2015 Page: 386-388

Online ISSN

0975-1491

Authors & Affiliations

V. R. Krishna Raju Mantena
Department of Pharmacology,Gland Institute of Pharmaceutical Sciences, Kothapet,Narsapur, Medak Dist, A. P.
India

G. Tejaswini
Department of Pharmacology,Gland Institute of Pharmaceutical Sciences, Kothapet,Narsapur, Medak Dist, A. P.
India


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