PHYTOCHEMICAL SCREENING, ANTIOXIDANT PROPERTIES IN VARIOUS EXTRACTS FROM THE LEAVES OF FLAGELLARIA INDICA L. FROM SABAH, MALAYSIA


Charles Gnanaraj, Muhammad Dawood Shah, A. T. M. Emdadul Haque, Mohammad Iqbal

Abstract


Objective: This study was conducted to evaluate the antioxidant capacities of the leaves of Flagellaria indica L. (FI) and its phytochemical constituents in six different extracts.

Methods: The assessment was done via a 2,2-diphenyl-1-picryl hydrazyl (DPPH) radical scavenging assay for the antioxidant test, the Folin-ciocalteau method for total phenolic content, Willet’s method for total flavonoid content and several other qualitative phytochemical tests carried out on all extracts.

Results: The results show the highest values of radical scavenging in the following order of extracts: butanol>ethyl acetate>aqueous>chloroform>methanol>hexane. The total phenolic content is the highest in the ethyl acetate (e. acetate) extract (153.28 mg/g) followed by butanol (134.78 mg/g), aqueous extract (65.88 mg/g), chloroform (55.28 mg/g), methanol (45.98 mg/g) and hexane (22.78 mg/g), expressed as gallic acid equivalents. The total flavonoids content was also the highest in e. acetate extract (38.96 mg/g) followed by butanol (28.45 mg/g), aqueous (21.18 mg/g), chloroform (12.9 mg/g), methanol (10.78 mg/g) and hexane extract (4.92 mg/g) using cathechin equivalents.

Conclusion: The antioxidant and radical scavenging activities of FI might be due to the strong presence of phenolic constituents, flavonoids and several other bioactive compounds. Thus, further research can be conducted to elucidate the potential of this plant for pharmacological importance.

 


Keywords


Flagellaria indica, Phenolic, Flavonoids, Radical scavenging activity, Bioactive compounds

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About this article

Title

PHYTOCHEMICAL SCREENING, ANTIOXIDANT PROPERTIES IN VARIOUS EXTRACTS FROM THE LEAVES OF FLAGELLARIA INDICA L. FROM SABAH, MALAYSIA

Keywords

Flagellaria indica, Phenolic, Flavonoids, Radical scavenging activity, Bioactive compounds

Date

11-07-2015

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Issue 9, 2015 Page: 510-512

Online ISSN

0975-1491

Authors & Affiliations

Charles Gnanaraj
Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MALAYSIA
Malaysia

Muhammad Dawood Shah
Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MALAYSIA
Malaysia

A. T. M. Emdadul Haque
niversity Kuala Lumpur, Royal College of Medicine Perak, Jalan Greentown, 30450 Ipoh, Malaysia
Malaysia

Mohammad Iqbal
Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, MALAYSIA
Malaysia


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