@article{Ruba_Mohan_2016, title={IN VITRO ANTIOXIDANT POTENTIAL OF WHOLE PLANT OF <em>ANDROGRAPHIS ECHIOIDES</em> (L.) NEES (ACANTHACEAE)}, volume={8}, url={https://journals.innovareacademics.in/index.php/ijpps/article/view/10544}, abstractNote={&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of the whole&lt;em&gt; &lt;/em&gt;plant of &lt;em&gt;Andrographis echioides&lt;/em&gt; have been tested using various antioxidant model systems viz; DPPH (1,1-Diphenyl-2-picryl-hydrazyl), hydroxyl, superoxide, ABTS (2, 2’-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic Acid) and reducing power.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Total phenolic content was estimated by folin-ciocalteau method. Flavonoids were determined by Aluminium chloride method. &lt;em&gt;In vitro&lt;/em&gt; antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts was evaluated by studying DPPH (1,1-Diphenyl-2-picryl-hydrazyl) radical scavenging activity, hydroxyl radical scavenging activity, superoxide radical scavenging activity, ABTS radical cation scavenging activity and reducing power using the standard procedure.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The total phenolic and flavonoids in methanol extract were found to be 1.26g/100 g and 1.18 g/100 g respectively. The methanol extract of &lt;em&gt;Andrographis echioides&lt;/em&gt; is found to possess DPPH, hydroxyl, superoxide and ABTS radical cation scavenging activity. The IC&lt;sub&gt;50 &lt;/sub&gt;value of DPPH, hydroxyl, superoxide, and ABTS radical cation scavenging activity were found to be 49.11, 36.18, 37.13 and 38.15 mg/ml respectively. Like the antioxidant activity, reducing the power of the extract increases with increase in concentration.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The finding indicated promising antioxidant activity of crude extracts of the above plant and needs further exploration for their effective are in the both modern and traditional system of medicines.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Keywords&lt;/strong&gt;:&lt;strong&gt; &lt;/strong&gt;Antioxidant activity, DPPH, ABTS, Phenol, Flavonoid.&lt;/p&gt;}, number={6}, journal={International Journal of Pharmacy and Pharmaceutical Sciences}, author={Ruba, A. Agnel and Mohan, V. R.}, year={2016}, month={Jun.}, pages={70–75} }