@article{A. Zintchem_Ndongo_Ngono Bikobo_Nkot_2014, title={BIOLOGICAL STUDIES ON NITROGEN - CONTAINING COMPOUNDS FROM CAMPYLOSPERMUM OLIVERIANUM AND CAMPYLOSPERMUM SULCATUM (OCHNACEAE)}, volume={6}, url={https://journals.innovareacademics.in/index.php/ijpps/article/view/2164}, abstractNote={<p><strong>Objective:</strong> <em>Campylospermum</em> <em>oliverianum</em> and <em>C</em>. <em>sulcatum</em> (Ochnaceae) are considered conspecific by some reports.</p> <p><strong>Methods:</strong> Following phytochemical analyses on those species, biological tests were carried.</p> <p><strong>Results:</strong> Phytotchemical analyses led to the isolation of three known nitrogenous compounds: two cyanoglucosides named dhurrin and menisdaurin and an indole alkaloid, serotobenine. These nitrogen-containing compounds showed potent cytotoxic activities against the microcrustacean <em>Artemia</em> <em>salina</em> (brine shrimp), when two of them exhibited efficient bactericidal effects against a few Gram cocci. This newest co-occurrence of both α- and γ-hydroxynitrile glucosides within the same species suggested another biosynthetic pathway for putative tyrosine-derived non-cyanogenic cyanoglucosides.</p> <p><strong>Conclusion:</strong> This study does not recommend an identical chemical profile for the two species, hence they might not be regarded as the same. The biosynthetic pathway of numerous putative tyrosine-derived cyanoglucosides is supported by the isolated compounds from <em>C</em>. <em>sulcatum</em>. The taxonomical value of serotobenine in species of the <em>Campylospermum</em> genus as well as the other one of cyanoglucosides in angiosperms is once more highlighted.</p>}, number={9}, journal={International Journal of Pharmacy and Pharmaceutical Sciences}, author={A. Zintchem, Auguste Abouem and Ndongo, Joseph Thierry and Ngono Bikobo, Serge Dominique and Nkot, Jeanne Louise}, year={2014}, month={Sep.}, pages={252–256} }