@article{DOWEK_FALLAH_BASHEER-SALIMIA_JAZZAR_QAWASMEH_2020, title={ANTIBACTERIAL, ANTIOXIDANT AND PHYTOCHEMICAL SCREENING OF PALESTINIAN MALLOW, MALVA SYLVESTRIS L.}, volume={12}, url={https://journals.innovareacademics.in/index.php/ijpps/article/view/39053}, DOI={10.22159/ijpps.2020v12i10.39053}, abstractNote={<p><strong>Objective: </strong>To evaluate antibacterial, antioxidant activities, the existence of the major secondary metabolites, and volatile compounds in methanolic extracts from <em>M. sylvestris </em>leaves.</p> <p><strong>Methods: </strong>Antibacterial activity was assessed using a well diffusion method. Antioxidant activity was assessed using ABTS<sup>●+</sup>and DPPH<sup>●</sup> free radical scavenging assays. Phytochemical screening for secondary metabolites and volatile compounds were done following standard techniques and gas chromatography-mass spectrometry (GC–MS).</p> <p><strong>Results: </strong>Methanolic extracts exhibited moderate antibacterial activity compared with the positive control against the gram-negative <em>Klebsiella pneumoniae </em>and the gram-positive bacteria’s <em>Staphylococcus aureus</em> by 47.2 and with 47.1% respectively. The average percentage of scavenging was 97.82±0.05 and 79.49±0.4 for ABTS<sup>•+</sup>and DPPH<sup>●</sup>, correspondingly. Total phenols were quantitatively estimated and found to be 78.9±9.55 mg GAE/g. Phytochemical screening assays revealed the presence of a wide range of phytochemical groups such as alkaloids flavonoids, phenols, tannins, quinones, saponins, steroids, tannins, terpenoides with at least sixteen volatile compounds detected in the plant.</p> <p><strong>Conclusion: </strong>The present study confirmed the antioxidant activity of the methanolic extract of <em>M. sylvestris</em> and the existence of is the volatile compounds (phytol), which mediate, even partially, the antioxidant and the claimed analgesic activity of the plant.</p>}, number={10}, journal={International Journal of Pharmacy and Pharmaceutical Sciences}, author={DOWEK, SAHAR and FALLAH, SEEMA and BASHEER-SALIMIA, REZQ and JAZZAR, MOHANNAD and QAWASMEH, ABDEL}, year={2020}, month={Oct.}, pages={12–16} }