@article{Phatak_Hendre_2016, title={GREEN SYNTHESIS OF SILVER NANORODS USING AQUEOUS EXTRACT OF KALANCHOE PINNATA FRESH LEAVES AND ITS SYNERGISTIC EFFECT WITH CIPROFLOXACIN AND ANTIBIOFILM ACTIVITIES}, volume={8}, url={https://journals.innovareacademics.in/index.php/ijpps/article/view/9281}, abstractNote={<p><strong>Objective: </strong>The present study was aimed to investigate antibacterial and antibiofilm activities of AgNPs alone and its combination with ciprofloxacin against various human pathogenic bacteria strains.<strong></strong></p><p><strong>Methods: </strong>Reproducible, energy efficient, eco-friendly green synthesis of silver nanoparticles (AgNPs) using aqueous extract of <em>Kalanchoe pinnata</em> fresh leaves based on photoirradiation was carried out. These photosynthesized AgNPs were characterized by infrared spectroscopy, scanning electron microscopy with energy dispersive X-ray spectroscopy, transmission electron microscopy, zeta potential, differential scanning calorimetry, differential thermal analysis and particle size analysis.</p><p><strong>Results: </strong>From the results, AgNPs showed the desired physicochemical properties in terms of optical, structural, thermal and photocatalytic properties. Also, it is observed that Gram-negative bacteria strains are more vulnerable to both AgNPs as well as conjugating ciprofloxacin with AgNPs rather than Gram-positive bacteria strains.</p><p><strong>Conclusion: </strong>Enhanced antibacterial effect was observed in the conjugation of ciprofloxacin with AgNPs rather than antibiotic or AgNPs alone. AgNPs showed an excellent inhibitory effect in the formation of biofilm.</p><p> </p>}, number={1}, journal={International Journal of Pharmacy and Pharmaceutical Sciences}, author={Phatak, Rohan Sharadanand and Hendre, Anup}, year={2016}, month={Jan.}, pages={168–174} }