TY - JOUR AU - Sasikala, K. AU - CHANDRA MOHAN, S. PY - 2014/08/31 Y2 - 2024/03/28 TI - TOTAL PHENOLIC, FLAVANOID CONTENTS AND GC-MS ANALYSIS OF CANTHIUM COROMANDELICUM LEAVES EXTRACT JF - International Journal of Pharmacy and Pharmaceutical Sciences JA - Int J Pharm Pharm Sci VL - 6 IS - 8 SE - Original Article(s) DO - UR - https://journals.innovareacademics.in/index.php/ijpps/article/view/1549 SP - 379-381 AB - <p><strong>Objective:</strong> In this study methanol extract of leaves of <em>canthium coromandelicum</em> (Family: Rubiaceae) was screened for the presence of phytochemical components by GC-MS analysis. In addition total phenolics and flavanoids were also estimated.</p><p><strong>Methods:</strong> GC-MS analysis of plant extract was performed using a Perkin-Elmer GC Clarus 500 system and Interpretation on mass spectrum GC-MS was conducted using the database of National Institute Standard and Technology (NIST).</p><p><strong>Result:</strong> 20 chemical compounds are identified from the plant extract. Squalene (C<sub>30</sub>H<sub>50</sub>) is the major component available at RT 23.10 and 15.02% peak area. Other most prevailing phytocomponds are Phytol, 25-desacetoxy- Cucurbitacin b, n-Hexadecanoic acid, Sitosterol etc., <em>Canthium coromandelicum</em> contained the total phenolic of 25.49±0.09 mg/g and the total flavonoids of 12.37±0.15mg/g which are equivalent to gallic acid and quercetin, respectively.</p><p><strong>Conclusion:</strong> The presence of various bioactive compounds justifies the use of <em>canthium coromandelicum</em> for various ailments by traditional practitioners.</p> ER -