SOLID LIPID NANOPARTICLES – A REVIEW


Manoj Kumar Sarangi, Sasmita Padhi

Abstract


Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical medicine and research, as well as in other varied sciences. Due to their unique size-dependent properties, lipid nanoparticles offer the possibility to develop new therapeutics. The incorporation of drugs into nanocarriers offers a new prototype in drug delivery that could be used for several levels of drug targeting. Hence, solid lipid nanoparticles hold great promise for reaching the goal of controlled and site specific drug delivery and hence have attracted wide attention of researchers. This review presents a broad treatment of solid lipid nanoparticles discussing their advantages, limitations and their possible remedies. Different production methods which are suitable for large scale production and applications of solid lipid nanoparticles are described. The characterization of solid lipid nanoparticles is generally carried out through photon correlation spectroscopy, scanning electron microscopy, differential scanning calorimetry etc.


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About this article

Title

SOLID LIPID NANOPARTICLES – A REVIEW

Date

02-07-2016

Additional Links

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Journal

Journal of Critical Reviews
Vol 3, Issue 3, 2016 Page: 5-12

Online ISSN

2394-5125

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Authors & Affiliations

Manoj Kumar Sarangi
Department of Pharmaceutical sciences, Sardar Bhagwan Singh Post Graduate Institute of Biomedical sciences and research, Balawala, Dehradun, Uttarakhand, India
India

Sasmita Padhi


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