EFFECT OF HYDROTHERMAL TEMPERATURE ON SYNTHESIS OF HYDROXYAPATITE FROM LIMESTONE VIA HYDROTHERMAL METHOD


Novesar Jamarun, Asregi Asril, Zulhadjri Zilfa, Upita Septiani

Abstract


Objective: In this study, the effect of hydrothermal temperature on the synthesis of hydroxyapatite (HAp) from limestone was investigated.

Methods: Precursors of limestone (CaCO3) and diammonium hydrogen phosphate ((NH4)2HPO4) with Ca/P ratio of 1.67 was mixed at pH 10 in order to synthesize hydroxyapatite by hydrothermal method. The solution was hydrothermally treated in an autoclave at various temperatures of 120, 160 and 200 °C for 24 h. Nano powder formed was then characterized.

Results: The hydroxyapatite obtained by hydrothermal method at various temperatures was characterized. The analysis of Fourier Transform Infrared (FTIR) revealed that HAp had phosphate (PO43-) and hydroxyl (O-H) groups although carbonate (CO32-) group remained. X-Ray Diffraction (XRD) revealed that the size of nanosize crystals was formed and then provided a large surface area. Scanning Electron Microscopy (SEM) results showed that HAp had a spherical shape. There was more agglomeration at 200 °C than at 160 °C. The ratio of the results of Energy Dispersive X-ray (EDX) analysis in 160 °C was 1.95 and at 200 °C was 1.71

Conclusion: The hydroxyapatite prepared at a temperature of 200 °C had smaller crystal size than the hydroxyapatite prepared at the temperatures of 120 and 160 °C. SEM pictures showed that the nanoparticle hydroxyapatite had a spherical shape.


Keywords


Hydroxyapatite, Limestone, Hydrothermal, Temperature, Nanoparticle

| PDF | HTML |

References


Dudek A, Adamczyk L. Properties of hydroxyapatite layers used for implant coating. Optica Aplicata 2013;43:143-51.

Bingol OR, Durucan C. Hydrothermal synthesis of hydroxyl-apatite from calcium sulfate hemihydrate. Am J Biomed Sci 2012;4:50-9.

Sobczak A, Kowalski Z, Wzorek Z. Preparation of Hydroxyapatite from animal bones. Acta Bioeng Biomech 2009; 11:23-8.

Wahl DA, Czernuszka JT. Collagen-Hydroxyapatite composites for hard tissue repair. Eur Cells Mater 2006;11:43-56.

Agrawal K, Singh G, Puri D, Prakash S. Synthesis and characterization of hydroxyapatite powder by sol-gel method for biomedical application. J Miner Mater Charact Eng 2011; 10:727-34.

Jamarun N, Azharman Z, Zilfa, Septiani U. Effect of firing for synthesis of hydroxyapatite by precipitation method. Orien J Chem 2016;32:2095-9.

Kolodziejczak-radzimska A, Samuel M, Paukszta D, Piasecki A, Jesionowski T. Synthesis of hydroxyapatite in the presence of anionic surfactant. Physicochem Probl Miner Process 2014; 50:225-36.

Sadjadi MS, Meskinfam M, Jagzdarreh H. Hydroxyapatite starch nano biocomposites synthesis and characterization. Int J Nano Dimens 2010;1:57-63.

Azharman Z, Arief S, Jamarun N, Sari TP, Asril A, Elfina S. Effect temperature for synthesis of hydroxyapatite from lime stone. Rasayan J Chem 2015;8:133-7.

Sari TP, Jamarun N, Syukri, Azharman Z, Asril A. Effect of mixing temperature on the synthesis of hydroxyapatite by sol-gel method. Orien J Chem 2014;30:1799-804.

Jamarun N, Yuwan S, Juita R, Rahayuningsih J. Synthesis and characterization carbonate apatite from bukit tui limestone padang Indonesia. J Appl Chem 2015;4:542-9.

Bhagwat M, Shah P, Ramaswamy V. Synthesis of nanocrystalline SnO2 powder by amorphous citrate route. Materials Lett 2003;57:1604-11.

Manyasree D, Peddi KM, Ravikumar R. Cuo nanoparticles: synthesis characterization and their bactericidal efficacy. Int J Appl Pharm 2017;9:71-4.

Meza D, Figueroa IA, Flores-morales C and pina-barb MC. Nano hydroxyapatite crystals obtained by colloidal solution. Rev Mex Fis 2011;57:471-4.

Palanivelu RA, Rubankumar. Synthesis and spectroscopic characterization of hydroxyapatite by sol-gel method. Int J ChemTech Res 2013;5:2965-9.

Raajshree KR, Durairaj B. Evaluation of the antityrosinase and antioxidant potential of zinc oxide nanoparticles synthesized from the brown seaweed-Turbinaria Conoides. Int J Appl Pharm 2017;9:116-20.

Abidi SA, Murtaza Q. Synthesis and characterization of nano-hydroxyapatite powder using wet chemical precipitation reaction. J Mater Sci Technol 2014;30:307-10.




About this article

Title

EFFECT OF HYDROTHERMAL TEMPERATURE ON SYNTHESIS OF HYDROXYAPATITE FROM LIMESTONE VIA HYDROTHERMAL METHOD

Keywords

Hydroxyapatite, Limestone, Hydrothermal, Temperature, Nanoparticle

DOI

10.22159/ijap.2018v10i1.23278

Date

06-01-2018

Additional Links

Manuscript Submission

Journal

International Journal of Applied Pharmaceutics
Vol 10, Issue 1 (Jan-Feb), 2018 Page: 136-139

Online ISSN

0975-7058

Statistics

78 Views | 23 Downloads

Authors & Affiliations

Novesar Jamarun
Department of Chemistry, Faculty of Mathematics and Social Sciences, Universitas Andalas, Padang, Indonesia
Indonesia

Asregi Asril
Department of Chemistry, Faculty of Mathematics and Social Sciences, Universitas Andalas, Padang, Indonesia

Zulhadjri Zilfa
Department of Chemistry, Faculty of Mathematics and Social Sciences, Universitas Andalas, Padang, Indonesia

Upita Septiani
Department of Chemistry, Faculty of Mathematics and Social Sciences, Universitas Andalas, Padang, Indonesia


Refbacks

  • There are currently no refbacks.