THE EFFECT OF CURCUMA XANTHORRHIZA - ETHANOL EXTRACT TO BIOFILM FORMATION OF STREPTOCOCCUS MUTANS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS (DENTAL BIOFILM RESEARCH: IN VITRO STUDY)


Fidhianissa . ., Hedijanti Joenoes, Ariadna A Djais

Abstract


Objective: This in vitro study aimed to analyze the mass ratio of single- and dual-species Streptococcus mutans and Aggregatibacter
actinomycetemcomitans biofilm after exposure to Curcuma xanthorrhiza ethanol extract (Xan).
Methods: A bacterial suspension in brain heart infusion medium, enriched with 0.2% sucrose, was exposed to the Xan, incubated for 18 hrs, and
analyzed using a crystal violet assay.
Results: This research concluded that the minimum inhibitory concentration of ethanol-temulawak extract against S. mutans was 5%, while the
minimum bactericidal concentration was 15%.
Conclusions: Xan prevented biofilm formation of single-species S. mutans and dual-species S. mutans and A. actinomycetemcomitans more effectively
than it did single-species A. actinomycetemcomitans.


Keywords


Biofilm formation, Single-species biofilm, Dual-species biofilm, Streptococcus mutans, Aggregatibacter actinomycetemcomitans, Curcuma xanthorrhiza ethanol extract, Crystal violet assay.

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About this article

Title

THE EFFECT OF CURCUMA XANTHORRHIZA - ETHANOL EXTRACT TO BIOFILM FORMATION OF STREPTOCOCCUS MUTANS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS (DENTAL BIOFILM RESEARCH: IN VITRO STUDY)

Keywords

Biofilm formation, Single-species biofilm, Dual-species biofilm, Streptococcus mutans, Aggregatibacter actinomycetemcomitans, Curcuma xanthorrhiza ethanol extract, Crystal violet assay.

DOI

10.22159/ijap.2017.v9s1.14_16

Date

30-10-2017

Additional Links

Manuscript Submission

Journal

International Journal of Applied Pharmaceutics
Vol. 9, Special Issue (Oct.), 2017 [PTMDS 2017] Page: 20-22

Online ISSN

0975-7058

Statistics

11 Views | 21 Downloads

Authors & Affiliations

Fidhianissa . .
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
Indonesia

Hedijanti Joenoes
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
Indonesia

Ariadna A Djais
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
Indonesia


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