EVALUATION OF ANTIBIOTIC USE IN 2018 AT THE KEBAYORAN BARU PRIMARY HEALTH CARE, INDONESIA, USING THE ANATOMICAL THERAPEUTIC CHEMICAL/DEFINED DAILY DOSE METHOD

  • LARASATI ARRUM KUSUMAWARDANI Clinical Pharmacy Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
  • ATIKA WAHYU PUSPITASARI Clinical Pharmacy Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
  • VANNISA NABILLA WIDYANTARI Clinical Pharmacy Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia

Abstract

Objective: The abnormally high use of antibiotics can indicate irrational prescribing. One of the ways by which to support rationally prescribing
antibiotics is by evaluating their frequency of use. This study aimed to evaluate the use of antibiotics in 2018 by outpatients at the Kebayoran Baru
Primary Health Care of Indonesia.
Methods: The study was a cross-sectional and descriptive design. Data were collected retrospectively from sampling outpatient records. The data were
on oral antibiotics prescribed in 2018 at Kebayoran Baru Primary Health Care. There were 10,553 prescriptions for oral antibiotics used as the study
samples. Both quantitative and qualitative evaluations were conducted. The quantitative evaluations were conducted using the method recommended
by the World Health Organization, namely, the anatomical therapeutic chemical/defined daily dose (DDD), and the qualitative evaluations were
conducted using the 90% drug utilization (DU 90%) method and the suitability of antibiotic use with the list of drugs in the Indonesian national
formulary for the first-level health facilities (FKTP).
Results: Three of the antibiotics used most often were amoxicillin at 0.9358 DDD/1000 inhabitants/d, ciprofloxacin at 0.4940 DDD/1000
inhabitants/d, and cefadroxil at 0.1983 DDD/1000 inhabitants/d. The drugs within the DU 90% segment were amoxicillin, ciprofloxacin, cefadroxil,
and thiamphenicol. There was 70% compatibility of antibiotic use with Indonesian national formulary for the FKTP.
Conclusion: We suggest that the use of antibiotics at Kebayoran Baru Primary Health Care tended to be on the high side and not in accordance with
national guidelines.

Keywords: Antibiotics, Anatomical therapeutic chemical/defined daily dose, 90% drug utilization method, Evaluation of drug use, the Indonesian national formulary

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KUSUMAWARDANI, L. A., PUSPITASARI, A. W., & WIDYANTARI, V. N. (2020). EVALUATION OF ANTIBIOTIC USE IN 2018 AT THE KEBAYORAN BARU PRIMARY HEALTH CARE, INDONESIA, USING THE ANATOMICAL THERAPEUTIC CHEMICAL/DEFINED DAILY DOSE METHOD. International Journal of Applied Pharmaceutics, 12(1), 78-82. https://doi.org/10.22159/ijap.2020.v12s1.FF011
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