Adsorptive removal of doxycycline from aqueous solution using graphene oxide/hydrogel Composite

  • waleed abdulsahib pharmacology


Doxycycline hydrochloride (D) belongs to a group of antibiotics known as tetracycline, which is related to the second generation and has twice the effectiveness of tetracycline. Important works have been advancing over a pollution of D antibiotic in aquatic environments in the last years. Graphene oxide (GO) is a low cost, eco friend and has a promising adsorbent effect on D, as well as it can be used efficiently to remove D from aqueous solution. Doxycycline adsorbs by a physical interactions on the surface of GO/ polyvinylpyrrolidone-acrylic acid composite (PVP-AAc) hydrogel composite. The adsorption kinetics correlated to pseudo-second-order model. Contact time studies of D equal to 180 min and high R2 value of 0.98 indicated that Langmuir isotherm model better fitted to the data for the removal of D at 15 °C. Thermodynamic parameters results pointed that the nature of adsorption process is physical, exothermic, ordered and spontaneous. The adsorption capacity of D favors the acidic media and it increases when adding NaCl to the solution. Graphene oxide/ PVP- AAc composite is a novel, good and efficient adsorbent for removal of the  doxycycline polluted the water , because of its low cost, hydrophilic properties, large surface area and special structure that give impressive dispersible activity in aquatic solutions.


Keywords: Key words: Doxycycline, Adsorption, Graphene oxide, composite and removal.
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abdulsahib, waleed. (2020). Adsorptive removal of doxycycline from aqueous solution using graphene oxide/hydrogel Composite. International Journal of Applied Pharmaceutics, 12(6). Retrieved from
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