• JEEVITAA KSHERSAGAR Department of Stem Cells and Regenerative Medicine, D. Y. Patil University, D. Y. Patil Vidyanagar, Kasba Bawda, Kolhapur 416006, MS, India
  • POONAM BEDGE Department of Stem Cells and Regenerative Medicine, D. Y. Patil University, D. Y. Patil Vidyanagar, Kasba Bawda, Kolhapur 416006, MS, India
  • RAKHI JAGDALE Department of Pathology, Shri Siddhivinayak Ganpati Cancer Hospital, Miraj, Sangli, MS, India
  • YASHWANT TORO Department of Scientific and Industrial Research Organization, Shri Siddhivinayak Ganpati Cancer Hospital, Miraj, Sangli, MS, India
  • SHIMPA SHARMA Department of Medicine, Dr. D. Y. Patil Medical College Kolhapur 416006, MS, India
  • MEGHNAD JOSHI Department of Stem Cells and Regenerative Medicine, D. Y. Patil University, D. Y. Patil Vidyanagar, Kasba Bawda, Kolhapur 416006, MS, India, Stem Plus Biotech Pvt. Ltd. SMK Commercial Complex, Bus Stand Road, Sangli, MS - 416416, India


Oral squamous cell carcinoma is a major public health concern worldwide and a growing threat for rapidly developing economies such as India, where it ranks among the top three cancers. This review aims to discuss the national status of oral cancer in terms of incidences and mortality. We have added the emphasis on clinical characteristics of oral potentially malignant disorders and emerging optical diagnostic techniques to detect oral lesions which would otherwise go undetected by a conventional oral examination. Modern detection systems such as autofluorescence, chemiluminiscence, Narrowband imaging and Raman spectroscopy will definitely aid Conventional oral examination for diagnosis. Definitive diagnosis of oral cancer by using saliva and serum-based noninvasive biomarkers can minimize the need of tissue biopsies and patient discomfort. Urgent research efforts are required to find new ways to identify and examine high-risk population for the early diagnosis and prevention of Oral squamous cell carcinoma.

Keywords: Biomarkers, Detection Methods, Early Diagnosis, Oral Squamous Cell Carcinoma


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KSHERSAGAR, J., BEDGE, P., JAGDALE, R., TORO, Y., SHARMA, S., & JOSHI, M. (2020). A REVIEW ON CURRENT SCENARIO OF ORAL CANCER IN INDIA WITH SPECIAL EMPHASIS ON MODERN DETECTION SYSTEMS AND BIOMARKERS. International Journal of Applied Pharmaceutics, 12(4), 1-10. https://doi.org/10.22159/ijap.2020.v12s4.40098
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