• IVAN SERGEEVICH IVANOV Department of Biotechnology and Industrial Pharmacy, MIREA-Russian Technological University, Moscow, Russia, 119454
  • ELENA OLEGOVNA BAKHRUSHINA Department of Pharmaceutical Technology, Sechenov University, Moscow, Russia, 119571
  • ANASTASIA ROMANOVNA TURAEVA Department of Pharmaceutical Technology, Sechenov University, Moscow, Russia, 119571
  • DENIS OLEGOVICH SHATALOV Department of Biotechnology and Industrial Pharmacy, MIREA-Russian Technological University, Moscow, Russia, 119454, JSC Institute of Pharmaceutical Technologies, Moscow, Russia 121353
  • ANNA VIKTOROVNA AYDAKOVA Department of Biotechnology and Industrial Pharmacy, MIREA-Russian Technological University, Moscow, Russia, 119454
  • DIANA ALEKSANDROVNA AKHMEDOVA Department of Biotechnology and Industrial Pharmacy, MIREA-Russian Technological University, Moscow, Russia, 119454
  • STANISLAV ANATOL’EVICH KEDIK Department of Biotechnology and Industrial Pharmacy, MIREA-Russian Technological University, Moscow, Russia, 119454



Ophthalmology, Packaging, Adherence to treatment, Compliance, Pharmionic


The purpose of this study is to find a unique ophthalmic packaging that takes into account modern requirements for both maintaining the quality and safety of the drug, compliance with therapy, and increasing the profitability and environmental friendliness of its production. Statistics from open international databases on drugs approved for ophthalmic therapy in 2022 are provided. The research criteria were a valid registration status, the type of packaging and the presence of a preservative in the composition of the eye drops. The results of statistical processing of databases of ministries of health of different countries have shown the relevance of monodose ophthalmic packaging, capable of long-term storage of the drug without preservatives. In many countries, particularly in Europe, many drugs in the form of a monodose containers are registered. On this basis, a unique aluminum-based monodose container design is proposed, eliminating the use of large quantities of plastic.


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