• M. Nagoor Meeran Department of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R and D Institute of Science and Technology (Deemed University), Avadi, Chennai, Tamil Nadu 600062, India
  • C. Hazarathaiah Yadav Department of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R and D Institute of Science and Technology (Deemed University), Avadi, Chennai, Tamil Nadu 600062, India
  • A. Zahir Hussain PG and Research Department of Chemistry, Jamal Mohamed College, Trichy, Tamilnadu 620020, India



Pyrazolines, Chalcone, Antioxidant, Antimicrobial, NMR


Objective: Pyrazolines are nitrogen-containing heterocyclic compounds with five-membered rings. They are fairly widely known, which is what sparked people's interest in this area of research to begin with. It has been shown that there are several ways to accomplish their synthesis. It has come to light that a great number of pyrazoline derivatives exhibit a wide variety of biological features.

Methods: The pyrazoline derivatives and the modified chalcone serve as the foundation for this research. Methods such as elemental analysis, infrared spectroscopy, nuclear magnetic resonance (1H and 13C), and mass spectrometry were used in order to analyze the structures of the produced compounds.

Results: The synthesis of chalcone (Furyl-Fluorenyl derivative) and the substituted pyrazolines was successful and analyzed enough by sophisticated techniques including NMR and Mass Spectrometry. The antibacterial and antioxidant capabilities of the compounds that were produced were also investigated and found the significant potential of the compounds.

Conclusion: The antibacterial and antioxidant capabilities of the compounds that were produced were also investigated and found the significant potential of the compounds.


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