• Suresh G. Killedar
  • Sachin S Salunkhe
  • Harinath N. More
  • Raviraj S. Karade
  • Suryakant V. Gaikwad
  • Sachin S. Mali


This paper describes the antibacterial and antifungal activities and Minimum Inhibitory Concentration (MIC) of different solvent (pet. ether, chloroform, ethyl acetate, acetone, methanol and water) extracts of leaves, bark, root and inflorescence of Memecylon umbellatum burm. The percent yields from leaves, bark, root and inflorescence was found to be 0.2062 to 2.836, 0.0601 to 0.5142, 0.050 to 1.425, 0.0210 to 0.717 respectively. Overall, acetone extract produced from the leaves exhibited significantly (P < 0.05) higher antibacterial activity along with superior antifungal activity. MIC for acetone and ethyl acetate extract of leaf was found to be 0.5 mg for the entire organisms compared to 3-15 mg for other extracts. Such study will explore pharmacological activity of the tested parts of Memecylon umbellatum burm especially, the leaves which might be valuable for therapeutic applications.


1. Kirtikar KR and Basu BD. Indian Medicinal Plants. 2nd ed. Popular Prakashan, New Delhi; 1996, p. 1063-67.
2. Nadkarni KM. Indian Materia Medica. 2nd ed. Bombay Prakashan, Bombay; 1982, p. 787.
3. Killedar SG, More HN Antimicrobial and Phytochemical Screening of Different Leaf Extracts of Memecylon umbellatum Burm. International Research Journal of Pharmacy 2012; 3(2): 188-192.
4. Sastri BN. The Wealth of India. Publication and Information Directorate, CSIR, Hillside, New Delhi, India; 1962, p. 336.
5. Dhar ML Screening of Indian plants for biological activity Part 1. Indian J. Exp. Biol 1968; 6(4): 232-247.
6. Killedar SG and More HN Screening of Antimicrobial Potential and Phytoconsituents for Different Extracts of Memecylon umbellatum Burm Inflorescences. Asian J. Pharm. Res 2011; 1(4): 114-118.
7. Killedar SG, More HN Antimicrobial potential and phytochemical screening of different bark extracts of Memecylon umbellatum burm. International Journal of Applied Microbiology Sciences 2012; 2(3): 50-58.
8. Amalraj T and Ignacimuthu S Evaluation of hypoglycemic effect of Memecylon umbellatum in normal and alloxan diabetic mice. J Ethanopharmacol 1998; 62(3): 247-250.
9. Joshi H Hypoglycemic effect of Memecylon umbellatum root, PHCOG MAG 2008; 4(15): 1-4.
10. Puratchikody and Naglakshmi G Wound healing activity of Memecylon umbellatum burm. J Plant Sci 2007; 2(2): 179-186.
11. Joshi H Evaluation of antipyretic potential of Memecylon umbellatum root extract. Indian J. Nat. Prod 2009; 25(1): 13.
12. Killedar SG, More HN Analgesic and anti-inflammatory studies of Memecylon umbellatum Burm roots in experimental animals. Research J. Pharm. and Tech 2009; 2(4): 858-861.
13. Joshi H Hepatoprotective activity of Memecylon umbellatum roots against acetaminophen induced hepatotoxicity in rats. J. Res. Educ. Indian Med 2008; 14(2): 49-54.
14. Killedar SG, More HN Anthelmintic and anti-Insect activities of Memecylon umbellatum Burm root extracts. Research J. Pharmacology and Pharmacodynamics 2010; 2(1): 54-58.
15. Ram PR, Mehrotra BN. Compendium of Indian Medicinal Plants. (Drug Research Preparative: A CDRI Series). Vol. 2. Central Drug Research Institute, Lucknow and Publications and Information Directorate, New Delhi; 1993, p.453.
16. Abdalfatah A, Christina YI, Saad Mohammed HA Antimicrobial Activity of Four Medicinal Plants Used by Sudanese Traditional Medicine. Journal of Forest Products & Industries 2013; 2(1): 29-33.
17. Borde VU, Pawar DP, Shelar SR, Apturkar RM Antimicrobial activity of some medicinal plants. Science Research Reporter 2013; 3(1): 33-37.
18. Harkare BR, Suryawanshi JS, Kadam SS, Osmani RA, Bhosale RR. Phytochemical analysis and antibacterial activity of methanolic seed extract of Memecylon umbellatum burm. IJPBS 2013; 3(2): 373-378.
19. Shahid W, Durrani R, Iram S, Durrani M, Khan FA Antibacterial activity in Vitro of medicinal plants. Sky Journal of Microbiology Research 2013; 1(2): 5-21.
20. Jamuna Bai A, Ravishankar Rai V, Pradeepa V Samaga Evaluation of the antimicrobial activity of three medicinal plants of South India. Malaysian Journal of Microbiology 2011; 7(1): 14-18.
21. Peach EK, Tracy MV. Modern Methods of Plant Analysis. Vol. III. Springer Verlag Publication; 1915, p. 332-350.
22. Harborne JB. A guide to Modern Techniques of Plant Analysis. 3rd ed. Chapman: Hall London; 1973.
23. British Pharmacopoeia. Vol. II. London HMSO; 1993, p. Appendix XID A-153.
24. Suresh G. Killedar, Harinath N. More, Raviraj S. Karade, Suryakant V. Gaikwad, Sachin S. Mali, Sachin S. Salunkhe et al. Phytochemical Screening and Evaluation Of Antimicrobial Activity of Different Root Extracts and Fractions of Memecylon umbellatum Burm. IJPRBS 2014; 3(1): 378-391.
25. Khandelwal KR. Practical Pharmacognosy -Techniques and Experiments. 18th ed. Nirali Prakashan : Pune 2007; p. 149-156.
26. Mahmood AM, Ameh JM In vitro antibacterial activity of Parkia biglobosa (Jacq.) root bark extract against some microorganisms associated with urinary tract infections. African Journal of Biotechnology 2007; 6(11): 1272-1275.
27. Manish BT, Rema S In Vitro Antimicrobial Activity of Stevia Rebaudiana Bertoni Leaves. Tropical Journal of Pharmaceutical Research 2006; 5(1): 557-560.
28. Parekh J, Chanda S In vitro antibacterial activity of the crude methanol extract of Woodfordia fruticosa Kurz. flower (Lythraceae). Brazilian Journal of Microbiology 2007; 38: 204-207.
29. Govt. of India Ministry of Health and family welfare, Indian Pharmacopoeia, vol. II, 1996 A-100-124.
30. Dagmar J, Katerina K, Ladislav K Screening for antimicrobial activity of some medicinal plants species of traditional Chinese medicine. Czech J Food Sci 2008; 21(3): 107-110.
31. Shabir G, Anwar F, Sultana B, Khalid ZM, Afzal M, Khan QM, Ashrafuzzaman M et al. Antioxidant and Antimicrobial Attributes and Phenolics of Different Solvent Extracts from Leaves, Flowers and Bark of Gold Mohar [Delonix regia (Bojer ex Hook.) Raf.]. Molecules 2011; 16: 7302-7319.
32. Sultana B. Anwar F. Ashraf M. Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 2009; 14: 2167-2180.
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How to Cite
G. Killedar, S., Salunkhe, S. S., N. More, H., S. Karade, R., V. Gaikwad, S., & S. Mali, S. (2014). COMPARATIVE IN-VITRO ANTIBACTERIAL AND ANTIFUNGAL ATTRIBUTES OF DIFFERENT SOLVENT EXTRACTS FROM LEAF, BARK, ROOT AND INFLORESCENCE OF MEMECYLON UMBELLATUM BURM. Innovare Journal of Ayurvedic Sciences, 2(2), 3-8. Retrieved from