Sangeeta Huidrom, R. K. Singh, Varsha Chaudhary


The alteration in the homeostasis of gut microbiota and harmful bacteria is associated with various kinds of diseases. Many gastrointestinal disorders such as inflammatory bowel diseases, irritable bowel syndrome, colorectal cancer and systemic diseases such as diabetes, obesity and atherosclerosis are due to dysbiosis in human gut. Many recent clinical studies revealed that probiotic is effective in treatment of various ailments by defending against colonization by opportunistic pathogens, production of antimicrobial substances and immunomodulation. Studies have shown that prebiotics and probiotics or the combinations of two i.e. synbiotics can restore the aberrant gut and can improve the health of gut. There is rapid growth and demand of dairy-based probiotics food in the market due to its awareness among the consumers. Bacteriotherapy has good hold future as novel therapy as consumers are looking for safe, cost effective and no adverse side effects therapeutic approach.

Keywords: Probiotics, Prebiotics, Gut microbiome, Synbiotics, Immunomodulation

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International Journal of Current Pharmaceutical Research
Vol 8, Issue 2, 2016 Page: 12-16

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Authors & Affiliations

Sangeeta Huidrom
Central Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun 248001, India

R. K. Singh
Central Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun 248001, India

Varsha Chaudhary
Central Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun 248001, India


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