A THERAPEUTIC JOURNEY OF MIXED LIGAND COMPLEXES CONTAINING 1,10-PHENANTROLINE DERIVATIVES: A REVIEW
Schiff bases have been exposed to reveal a wide range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Mixed ligand complexes can be a synthetic challenge to tune the properties of the transition metal complexes. The review of this paper covers updated information on the most active mixed ligand metal complexes of 1,10-phenantroline derivatives that have been reported to prove considerable pharmacological actions such as, antifungal, antibacterial, antitumor, antimalarial, antiviral and other biological activities. In the present study, we summarized the biological aspects, chemistry and applications of some important mixed ligand complexes. This review is balancing to earlier reviews and aims to review the work reported on various biological activities of mixed ligand complexes bearing 1,10-phenantroline derivatives from year 2000 to the beginning of 2016.Keywords: 1,10-phenanthroline, Mixed ligand complexes, Antibacterial investigation, Antifungal investigation, Antitumor investigation
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