A THERAPEUTIC JOURNEY OF MIXED LIGAND COMPLEXES CONTAINING 1,10-PHENANTROLINE DERIVATIVES: A REVIEW


Rajkumar Mahalakshmi, Natarajan Raman

Abstract


Schiff bases have been exposed to reveal a wide range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Mixed ligand complexes can be a synthetic challenge to tune the properties of the transition metal complexes. The review of this paper covers updated information on the most active mixed ligand metal complexes of 1,10-phenantroline derivatives that have been reported to prove considerable pharmacological actions such as, antifungal, antibacterial, antitumor, antimalarial, antiviral and other biological activities. In the present study, we summarized the biological aspects, chemistry and applications of some important mixed ligand complexes. This review is balancing to earlier reviews and aims to review the work reported on various biological activities of mixed ligand complexes bearing 1,10-phenantroline derivatives from year 2000 to the beginning of 2016.

Keywords: 1,10-phenanthroline, Mixed ligand complexes, Antibacterial investigation, Antifungal investigation, Antitumor investigation

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About this article

Title

A THERAPEUTIC JOURNEY OF MIXED LIGAND COMPLEXES CONTAINING 1,10-PHENANTROLINE DERIVATIVES: A REVIEW

Date

01-07-2016

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Journal

International Journal of Current Pharmaceutical Research
Vol 8, Issue 3, 2016 Page: 1-6

Online ISSN

0975-7066

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Authors & Affiliations

Rajkumar Mahalakshmi
Research Department of Chemistry, VHNSN College, Virudhunagar 626001, India
India

Natarajan Raman
Research Department of Chemistry, VHNSN College, Virudhunagar 626001, India


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