FORMULATION AND BIO-AVAILABILITY PARAMETERS OF PHARMACEUTICAL SUSPENSION


Pakpi Doye, Tanya Mena, Nilimanka Das

Abstract


The suspension is a biphasic liquid or semi-solid dosage form where the finely divided insoluble solid drug particles are homogeneously dispersed in a liquid or semi-solid medium. The solid drug particles act here as the dispersed phase and the liquid or the semi-solid as the dispersion medium. Suspensions contribute to pharmaceutical dosage form development by supplying drugs that are insoluble in all acceptable medium and often distasteful. Suspension translates such drugs into more bio-available form when compared to capsules, tablets, coated tablets, enteric coated tablets and sustained release products. The dosage form is palatable to the patient and many are doing well when applied to the skin or mucous membrane. This particular dosage form is also applied for injecting drugs into the systemic circulation. Therefore, pharmaceutical suspension finds its application through three different routes of administration namely oral, externally applied suspension and injectable one. The success of any dosage form largely depends on formulation parameters and the factors that influence the bioavailability which ultimately dictate the therapeutic success of the formulated dosage form. Hence, it is obvious to discuss the formulation parameters and the factors influencing bioavailability of suspension for the therapeutic success of it.


Keywords


Formulation, Flocculation, Structured vehicles, Bio-availability factors

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References


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About this article

Title

FORMULATION AND BIO-AVAILABILITY PARAMETERS OF PHARMACEUTICAL SUSPENSION

Keywords

Formulation, Flocculation, Structured vehicles, Bio-availability factors

DOI

10.22159/ijcpr.2017.v9i3.18892

Date

05-05-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 3, 2017 Page: 8-14

Online ISSN

0975-7066

Statistics

171 Views | 815 Downloads

Authors & Affiliations

Pakpi Doye
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala 799005, Tripura, India

Tanya Mena
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala 799005, Tripura, India

Nilimanka Das
Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala 799005, Tripura, India


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