APPLICATION OF METAL COMPLEXES OF SCHIFF BASES AS AN ANTIMICROBIAL DRUG: A REVIEW OF RECENT WORKS


Kumble Divya, Geetha M. Pinto, Asha F Pinto

Abstract


Schiff bases are versatile ligands which are synthesized from the condensation of primary amines with carbonyl groups. Synthesis of Schiff base transition metal complexes by using Schiff base as ligands appears to be fascinating in view of the possibility of obtaining coordination compounds of unusual structure and stability. These transition metal complexes have received exceptional consideration because of their active part in metalloenzymes and as biomimetic model compounds due to their closeness to natural proteins and enzymes. These compounds are very important in pharmaceutical fields because of their wide spectrum of biological activities. Most of them show biological activities including antibacterial, antifungal, antidiabetic, antitumor, antiproliferative, anticancer, herbicidal, and anti-inflammatory activities. The biological activity of the transition metal complexes derived from the Schiff base ligands has been widely studied. This review summarizes the importance, Scope and antimicrobial activities of Schiff base metal complexes.


Keywords


Schiff bases, Metal complexes, Microorganism and antimicrobial activity

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References


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About this article

Title

APPLICATION OF METAL COMPLEXES OF SCHIFF BASES AS AN ANTIMICROBIAL DRUG: A REVIEW OF RECENT WORKS

Keywords

Schiff bases, Metal complexes, Microorganism and antimicrobial activity

DOI

10.22159/ijcpr.2017.v9i3.19966

Date

05-05-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 3, 2017 Page: 27-30

Online ISSN

0975-7066

Statistics

110 Views | 148 Downloads

Authors & Affiliations

Kumble Divya
Department of Post Graduate Studies and Research in Chemistry, St. Agnes College, Mangaluru 575002, Karnataka, India

Geetha M. Pinto
Department of Post Graduate Studies and Research in Chemistry, St. Agnes College, Mangaluru 575002, Karnataka, India

Asha F Pinto
Department of Post Graduate Studies and Research in Chemistry, St. Agnes College, Mangaluru 575002, Karnataka, India


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