DRUG UTILISATION STUDY OF STROKE AND OTHER PATIENTS ADMITTED TO GENERAL WARD OF NEUROLOGY UNIT AT QUATERNARY CARE PRIVATE HOSPITAL


LAXMAN WAGLE, ABEL ABRAHAM THOMAS, SUNIL SHRESTHA

Abstract


Objective: To study the profile of the patient, the pattern of their illness and their drug use patterns attending to general ward of quaternary care hospital.

Methods: Prospective observational study of 2 mo was performed at neurology unit of the quaternary care private hospital, India. Patients aged above 20 y with at least one neurological drug in prescription were included to observe their demographic profile, illness pattern and drug use. The data was analysed and summarised as frequency and percentage using microsoft excel and presented as tables.

Results: Among 60 patient that were enrolled, more were males (N=33, 55%) than females (N=27, 45%) and within the age group of 60-70 y (N=22, 36.67%). The majority of patients were diagnosed with strokes (N= 48, 80%) where the cerebrovascular accident was most common (N=16, 26.66%). Males (N=29, 60.4%) were more prone to get stroke than females (N=19,39.6%). An average number of drugs per prescription was 5.7, the percentage of antibiotics, generic drugs and injections were 36.6%, 0.05% and 44.14% respectively. A total of 28 different drug classes with 61 different drugs was utilised. Fourteen drug classes had been accounted for 90% of drugs utilisation. Clopidegrol+Aspirin have frequently used the drug.

Conclusion: Most people attending neurology unit were elderly. Stroke occupies 1st list for the burden. Average drugs for neurology visit remain high. Wide types of drug classes are utilised in neurological wards.


Keywords


Neurology department, Drug utilisation, Profile of stroke patients

| PDF |

References


Burton KJ, Allen S. A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant. Ann Trop Pediatric 2003;23:139–43.

Raina SK, Razdan S, Nanda R. Prevalence of neurological disorders in children less than 10 y of age in RS Pura town of Jammu and Kashmir. J Pediatr Neurosci 2011;6:103–5.

WHO report-Neurological disorder, public health challenge; 2006.

http://www.medscape.org/neurology. [Last accessed on 15 Dec 2016]

Introduction to Drug Utilization Research by World Health Organization; 2013.

Chowdhury RN, Hasan H, Rahman YU, Khan IS, Hussain AR, Ahsan S. Pattern of neurological disease seen among patients admitted in tertiary care hospital. BMC Res Notes 2014;7:1-5.

Gajurel BP, Parajuli P, Nepali R, Oli KK. Spectrum of neurological disorders admitted in Tribhuvan University Teaching Hospital Maharajgunj. J Inst Med 2012;34:50–3.

Costello DJ, Renganathan R, Hare AO, Murray B, Lynch T. Audit of an inpatient neurology consultation service in a tertiary referral centre: the value of the consulting neurologist. Ir Med J 2005;98:134–7.

Abbasi YM, Ali MA. Prescribing pattern of drugs in strokes patients. Arch Pharm Pract 2012;3:283-8.

Vurumadla S, Rakshith V, Murari CH, Venkateshwarlu K. A study on symptoms, risk factors and prescribing pattern of drugs used in stroke patients. Int J Pharm Pharm Sci 2015;7:421-6.

Eapen RP, Parikh JP. A study on clinical profile and risk factor of cerebrovascular stroke. Gazi Med J 2009;64:47-54.

Naik M, Rauniyar RK. Clinicoradiological profile of stroke in eastern Nepal: a computed tomographic study. Kathmandu University Med J 2006;4:161-6.

Kumar SV, Damodar G, Ravikanth S, Vijayakumar G. Drug utilization pattern of stroke patients in a tertiary care hospital. Int J Curr Pharm Clin Res 2012;2:3-7.

Mathew JR, Cheryl DB, George H. Sex differences in stroke, epidemiology, clinical presentation, medical care and outcomes. Lancet Neurol 2008;7:915-26.

Murray CJL, Lopez AD. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020. 1st edition. Harvard University Boston: The Harvard school of public health on behalf of the world health organization and the World Bank; 1996.

Weatherall MW. Acute neurology in a twenty-first-century district general hospital. J R Coll Physicians Edinb 2006;36:196–200.

Chapman FA, Pope AE, Sorensen D, Knight RS, Salman ASR. The uses of a rapid access neurology clinic. J R Coll Physicians Edinb 2009;39:296–300.

Athira J, Chaithanya KT, Joffey SJ, Kavitha SP, Sambath KR. A prospective study of drug–drug interactions and adverse drug reactions among stroke patients in a tertiary care hospital. Asian J Pharm Clin Res 2016;9 Suppl 3:100-4.

Kuriakose C, Shifafiya MN, Sekar V, Sambath KR. To evaluate the prevalence and drug prescribing trends in stroke patients: a retrospective study. Int J Chem Pharm Sci 2014;5:22-7.

Silverman IE. Post-stroke seizures. Arch Neurol 2002;59:194-202.

Kanji S, Corman C, Douen AG. Blood pressure management in acute stroke: comparison of current guidelines with prescribing patterns. Can J Neurol Sci 2002;29:125-31.

Po HL, Lin YJ, Hseuh IH. The prescribing patterns of antithrombotic agents for prevention of recurrent ischemic stroke. Acta Neurol Taiwan 2009;18:98-103.

Andhuvan G, Ayyappan P, Sahana C, Poovizhi S, Sivasakthi K. Knowledge of modifiable risk factors of heart disease among patients with cardiovascular ris. Asian J Pharm Clin Rres 2017;10:99-102.




About this article

Title

DRUG UTILISATION STUDY OF STROKE AND OTHER PATIENTS ADMITTED TO GENERAL WARD OF NEUROLOGY UNIT AT QUATERNARY CARE PRIVATE HOSPITAL

Keywords

Neurology department, Drug utilisation, Profile of stroke patients

Date

09-06-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Article in press [Scheduled in July, 2017] Page:

Online ISSN

0975-7066

Statistics

3 Views | 18 Downloads

Authors & Affiliations

LAXMAN WAGLE
Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, BG Nagara, Mandya District, Karnataka India, 571448,

ABEL ABRAHAM THOMAS
Department of Pharmacy Practice, Sri Adichunchanagiri College of Pharmacy, BG Nagara, Mandya District, Karnataka India, 571448,

SUNIL SHRESTHA
Department of Pharmacy, Kathmandu University, Kavre, Nepal


Refbacks

  • There are currently no refbacks.