PHYTOCHEMICAL PROFILING AND ANTIBACTERIAL EFFICACY SCREENING OF AGLAIA MALABARICA SASIDH


Archana Elamkulam Ravindran, John Ernest Thoppil

Abstract


Objective: Aglaia malabarica is an unexplored endemic forest tree belonging to the family Meliaceae. The present study was conducted to screen the phytochemical constituents of the leaf extract, to analyze the important secondary metabolites and to determine the antibacterial efficacy of the plant extract.

Methods: Antibacterial activity was studied using agar based disc diffusion method. Four strains of bacteria were used for the antibacterial study that includes Staphylococcus aureus, Pseudomonas aeruginosae, Proteus vulgaris and Bacillus megaterium.

Results: The presence of constituents like, carbohydrates, proteins, tannins, phenols, terpenoids, flavonoids, alkaloids and steroids were confirmed. Saponin was found to be absent. The secondary metabolites quantified were terpenoids, phenols and flavanoids, which were found in considerable amounts. The minimum inhibitory concentration (MIC) of all the bacteria studied was found to be 500 µg methanolic leaf extract.

Conclusion: The plant extract was found to be highly potent against both the Gram positive and Gram negative strains and this property may be attributed to the potent phytochemicals revealed in the extract.


Keywords


Aglaia, Antibacterial, Meliaceae, Secondary metabolites, Leaf extract, Phytochemicals

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About this article

Title

PHYTOCHEMICAL PROFILING AND ANTIBACTERIAL EFFICACY SCREENING OF AGLAIA MALABARICA SASIDH

Keywords

Aglaia, Antibacterial, Meliaceae, Secondary metabolites, Leaf extract, Phytochemicals

DOI

10.22159/ijcpr.2018v10i1.24402

Date

15-01-2018

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 10, Issue 1 (Jan-Feb), 2018 Page: 20-22

Online ISSN

0975-7066

Statistics

41 Views | 3 Downloads

Authors & Affiliations

Archana Elamkulam Ravindran
Cell and Molecular Biology Division, University of Calicut, Kerala, India
India

John Ernest Thoppil
Cell and Molecular Biology Division, University of Calicut, Kerala, India
India


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