ANALYSIS OF ADVERSE DRUG REACTIONS SPONTANEOUSLY REPORTED TO ADVERSE DRUG MONITORING CENTRE OF A TERTIARY CARE HOSPITAL–PROSPECTIVE STUDY


Gajanan P. Kulkarni, Lokesh V. Patil

Abstract


Objective: To assess ADRs with reference to causative drugs, organ systems involved and seriousness of reactions.

Methods: A prospective study conducted over a period of 1 y. The spontaneous adverse drug reactions reported between July 2016 and July 2017 at AMC centre BRIMS, Bidar were analyzed using Naranjo’s scale. Causality assessment of suspected drugs involved, system affected, and seriousness of reactions was assessed.

Results: GIT system was most commonly involved, followed by generalized features, skin and appendages, CNS i. e, extrapyramidal system and dizziness, hearing and vestibular systems.

Conclusion: Majority of the ADRs reported were mild to moderate severity and 20% can be categorized as severe reactions, which needed to treat under hospitalization


Keywords


Adverse drug reaction, Pharmacovigilance, Causality assessment, Serious reactions

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About this article

Title

ANALYSIS OF ADVERSE DRUG REACTIONS SPONTANEOUSLY REPORTED TO ADVERSE DRUG MONITORING CENTRE OF A TERTIARY CARE HOSPITAL–PROSPECTIVE STUDY

Keywords

Adverse drug reaction, Pharmacovigilance, Causality assessment, Serious reactions

DOI

10.22159/ijcpr.2018v10i1.24403

Date

15-01-2018

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 10, Issue 1 (Jan-Feb), 2018 Page: 23-25

Online ISSN

0975-7066

Statistics

27 Views | 2 Downloads

Authors & Affiliations

Gajanan P. Kulkarni
Department of Pharmacology, Bidar Institute of Medical Sciences (BRIMS), Bidar, Karnataka
India

Lokesh V. Patil
Department of Pharmacology, Bidar Institute of Medical Sciences (BRIMS), Bidar, Karnataka
India


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