TOXICITY OF ATRAZINE AND RELATED TO TESTICULAR, TISSUE DAMAGING ENZYME LEVELS IN POECILIA SPHENOPS


S. Vasanth, G. Bupesh, T. Siva Vijayakumar, P. Subramanian, P. Ramasamy

Abstract


Objective: This study was designed to evaluate the toxic effects of Atrazine (ATZ) on the enzyme levels in Poecilia sphenops.

Methods: The cytosolic testicular enzyme and tissue-damaging enzyme activity were measured in Poecilia sphenops was exposed to 3 sub-lethal concentrations (1.25, 2.5 and 5 mg/l) of atrazine for 100days and control was also maintained. The toxic effects of ATZ to Poecilia sphenops were assessed through testicular marker enzyme, tissue-damaging enzyme level.

Results: The activities of testicular functional enzyme ALP, ACP, SDH, LDH, G6PDH and tissue-damaging the activities of glutamate oxaloacetic transaminase (GOT) and glutamate pyruvic transaminase (GPT) activity levels were altered in treated groups compared with that of the control.

Conclusion: This study demonstrates that atrazine induces tissue damage in terms of enhanced enzyme activity and testicular enzyme activity in Poecilia sphenops. Atrazine has toxicity to the reproductive system in Poecilia sphenops.


Keywords


Atrazine, Poecilia sphenops, Testicular Marker, ALP, ACP, SDH, LDH, G6PDH, GPT GOT

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About this article

Title

TOXICITY OF ATRAZINE AND RELATED TO TESTICULAR, TISSUE DAMAGING ENZYME LEVELS IN POECILIA SPHENOPS

Keywords

Atrazine, Poecilia sphenops, Testicular Marker, ALP, ACP, SDH, LDH, G6PDH, GPT GOT

DOI

10.22159/ijcpr.2018v10i2.25875

Date

15-03-2018

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 10, Issue 2 (Mar-Apr), 2018 Page: 75-80

Online ISSN

0975-7066

Authors & Affiliations

S. Vasanth
Central Research Laboratory, Sree Balaji Medical College and Hospital, Chrompet, Chennai 600044, Tamil Nadu, India, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024

G. Bupesh
Central Research Laboratory, Sree Balaji Medical College and Hospital, Chrompet, Chennai 600044, Tamil Nadu, India, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024

T. Siva Vijayakumar
Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024, PG and Research Department of Biotechnology, Srimad Andavan College of Arts and Science, Thiruvanaikovil, Thiruchirappalli-05. Tamil Nadu, India

P. Subramanian
Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024

P. Ramasamy
Central Research Laboratory, Sree Balaji Medical College and Hospital, Chrompet, Chennai 600044, Tamil Nadu, India


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