EVALUATION OF DRUG-DRUG INTERACTIONS IN PATIENTS OF GENERAL MEDICINE, ICU and EMERGENCY DEPARTMENTS AT A TERTIARY CARE HOSPITAL


N. Vanitha Jyothi, Bharathi D. R., Prakruthi G. M.

Abstract


Objective: To evaluate the drug-drug interactions in General medicine, ICU and Emergency departments.

Methods: It is a prospective-observational study. This study included hospital In-patients treated in General medicine, ICU and Emergency. Data were collected from the medical records of In-patients which includes patient’s demographic details, medical history, social history, treatment chart, status and drug-drug interaction is assessed by using Lexicompand Medscape and other tertiary resources and documented in a suitably designed data collection form.

Results: A total of 250 subjects were enrolled in the study. The majority (23.6%) of cases were identified in the age group 51–60 y old. Higher rate of DDIs was identified in the male gender prescriptions. 70% moderate interactions, 33.6% Minor interactions, 6.4% serious interaction found in General medicine, ICU and Emergency departments.

Conclusion: Polypharmacy, age and comorbid condition were took part major role in drug-drug interactions.


Keywords


Drug-drug interaction, Significant, Minor, Serious interactions

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About this article

Title

EVALUATION OF DRUG-DRUG INTERACTIONS IN PATIENTS OF GENERAL MEDICINE, ICU and EMERGENCY DEPARTMENTS AT A TERTIARY CARE HOSPITAL

Keywords

Drug-drug interaction, Significant, Minor, Serious interactions

DOI

10.22159/ijcpr.2018v10i3.27345

Date

17-05-2018

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 10, Issue 3 (May-June), 2018 Page: 68-71

Online ISSN

0975-7066

Authors & Affiliations

N. Vanitha Jyothi
Pharm D, Department of Pharmacy Practice, SJM College of Pharmacy, Chitradurga, Karnataka, India, 577502

Bharathi D. R.

Prakruthi G. M.


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