EVALUATION OF STABILITY OF HERBAL ANTI-ACNE GEL FORMULATION
Objective: The present study was aimed to evaluate the physical and chemical stability of prepared gel formulations at various intervals for a period of one year.
Methods: The amount of total flavonoids was analysed using aluminium chloride colorimetric assay using rutin as standard. Gels were dissolved in distilled water and then analysis was carried out and flavonoids quantified by U. V at a wavelength of 415 nm.
Results: Flavanoid content were examined at various time intervals and rate of drug degradation was calculated graphically and by using arrhenius equation. The shelf life of the prepared gel F1, F2, F3, and F4 was found to be 291.76, 460, 184 and 148.39 d.
Conclusion: In the present study an attempt has been made to evaluate the shelf life of herbal gel formulations and to generate scientific database for formulation and evaluation of herbal products.
2. Jain KL, Choudhury PK, Sharma M, Dev S. Preparation and evaluation of anti-acne herbal gel. Eur J Biomed Pharm Sci 2017;4:578-81.
3. Yapar EA, Inal O. Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil. Acta Pharm 2013;63:531-43.