EVALUATION OF STABILITY OF HERBAL ANTI-ACNE GEL FORMULATION

Kajal L. Jain; P. K. Choudhury; Maya Sharma

doi:10.22159/ijcpr.2019v11i1.31990

Authors

Kajal L. Jain Department of Pharmaceutical Sciences, New Campus, Mohanlal Sukhadia University, Udaipur 313001(Rajasthan), India
P. K. Choudhury Department of Pharmaceutical Sciences, New Campus, Mohanlal Sukhadia University, Udaipur 313001(Rajasthan), India
Maya Sharma Department of Pharmaceutical Sciences, New Campus, Mohanlal Sukhadia University, Udaipur 313001(Rajasthan), India

DOI:

https://doi.org/10.22159/ijcpr.2019v11i1.31990

Keywords:

Stability, Shelf life, Herbal gel, Evaluation

Abstract

Objective: The present study was aimed to evaluate the physical and chemical stability of prepared gel formulations at various intervals for a period of one year.

Methods: The amount of total flavonoids was analysed using aluminium chloride colorimetric assay using rutin as standard. Gels were dissolved in distilled water and then analysis was carried out and flavonoids quantified by U. V at a wavelength of 415 nm.

Results: Flavanoid content were examined at various time intervals and rate of drug degradation was calculated graphically and by using arrhenius equation. The shelf life of the prepared gel F1, F2, F3, and F4 was found to be 291.76, 460, 184 and 148.39 d.

Conclusion: In the present study an attempt has been made to evaluate the shelf life of herbal gel formulations and to generate scientific database for formulation and evaluation of herbal products.

Downloads

Download data is not yet available.

References

Jain KL, Choudhury PK, Sharma M. Total flavonoid quantification and to study antibacterial potency of extracts of butea monosperma flowers, nigella sativa seeds and vitex agnus castus leaves. Int J Curr Pharm Res 2017;9:71-4.

Jain KL, Choudhury PK, Sharma M, Dev S. Preparation and evaluation of anti-acne herbal gel. Eur J Biomed Pharm Sci 2017;4:578-81.

Yapar EA, Inal O. Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil. Acta Pharm 2013;63:531-43.