SCIENTIFIC VALIDATION AND STANDARDIZATION OF PARPATAKA AN AYURVEDIC DRUG WITH RESPECT TO FUMARIA INDICA
Keywords:Parpataka drug, Fumaria indica, Macro and microscopical studies
Objective: Fumaria indica is an essential curative herb and asserted as a prevalent weed across the plains of India. The entire plant is popularly employed in conventional systems of medicine for its therapeutic activities like anthelmintic, diuretic, diaphoretic, laxative, purging and stomachic. The entire plant is regarded to have therapeutical purposes in Ayurvedic and Unani systems of medicine and is employed in the preparation of important Ayurvedic formulation Parpataka. In Unani systems of medicine, it is used as shahtara. This contemporary study is intended to authenticate and validate the species Fumaria indica with respect to Parpataka drug.
Methods: The chief objective of this contemporary research work is to assess the various pharmacognostic properties like Macroscopical, Microscopical, Physiochemical and Fluorescence studies. Microscopical studies include cell structure and their arrangement, Physicochemical parameter s include loss on drying, total ash value, acid insoluble ash, water-insoluble ash, various extractive values etc. Qualitative tests for various functional groups were also carried out.
Results: The microscopical characters of leaf, stem and roots, physicochemical, preliminary phytochemical profiles were established.
Conclusion: The pharmacognostical screening on Fumaria indica is significant data for the identification and to determine the quality and purity of the plant material in future reviews.
2. Nadkarni AK. Indian Materia Medica, Bombay; 1954.
3. Bapalal V. Some controversial drugs in Indian Medicine, Chowkambha, Varanasi; 1982.
4. Anonymous. The Wealth of India (Raw materials) C. S. I. R, New Delhi. Vol. IV; 1956. p. 68-141.
5. Yoganarasimhan SN. Medicinal plants of India, Karnataka, Interline Publishing Private Limited, Bangalore; 1996.
6. Kirtikar KR, Basu D. Indian medicinal plants with illustrations, Dehradun, Uthranchal. Vol II, V, VIII; 2003. p. 328, 1650, 1651, 1652, 2613, 2626, 2677.
7. Anonymous. The Ayurvedic Formulary of India. Pt-I Controller of Publications, New Delhi; 1978.
8. Kapoor SL, Mitra R. Herbal drugs in Indian pharmaceutical industry, Lucknow; 1979.
9. Chunekar KC. Bhavaprakasanighantu, Chowkambha Bharati Academy Varanasi; 1982. p. 323-7.
10. Kirtikar KR, Basu D. Indian Medicinal Plants, Allahabad; 1918.
11. Sass JE. Elements of botanical microtechnique. Mc Graw Hill Book Co. New York; 1940. p. 222-6.
12. Esau and Katherine. Anatomy of Seed Plants. John Wiley and Sons, New York; 1977. p. 767.
13. Gibbs RD. Chemotaxonomy of flowering plants. Vol. 1-7. McGill Queen’s University Press: London; 1974.
14. Harborne JB. Phytochemical methods. A guide to modern techniques of plant analysis. (3rd edition) Chapman and Hall Publications, London; 1973.
15. Johansen DA. Plant microtechnique. New York: McGraw-Hill Book Company, Inc; 1940.
16. Gokhale SB, Kokate CK. Practical pharmacognosy. (13th edition). Nirali Prakashan; 2009.
17. Kokoski CJ, Kokoski RJ, Salma FJ. Fluorescence of powdered vegetable drugs under ultra-violet radiation. J Am Pharm Asson 1958;47:715-7.
18. Penchala Pratap G, Sudarsanam G, Prasad GP. Microscopical observations on cissus vitiginea L. Int J Ayur Pharma Res 2014;2:47-58.
19. Anonymous. Pharmacopoeia of India (Repr. Edition). Controller of Publications, New Delhi; 1985.
20. Anonymous. Phytochemical investigation of certain medicinal plants used in Ayurveda, Central Council for Research in Ayurveda and Siddha, New Delhi; 1990.
21. Chase CR, Pratt RJ. Fluorescence of powdered vegetable drugs with particular resource to the development of a system of identification. J Am Pharm Assoc 1949;38:324-31.
22. Sayeeduddin M. A further contribution to some of the common flowering plants of Hyderabad State, their distribution and economic importance. J Bombay Nat Hist Soc 1938;40:191-212.
23. Venkaiah M. Studies on the vegetation and flora of Vijayanagaram district. Ph. D Thesis, Andhra University, Visakhapatnam; 1980.