FABRICATION AND EVALUATION OF HERBAL TRANSDERMAL FLIM FROM HIBISCUS ROSA SINENSIS

  • S. DHANALAKSHMI Department of Pharmacognosy, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077
  • N. HARIKRISHNAN Department of Pharmaceutical Chemistry and Analysis, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077
  • M. DEVI Department of Pharmacology, Faculty of Pharmacy, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077
  • V. KEERTHANA Faculty of Pharmacy, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077
  • VIJAYALAKSHMI Faculty of Pharmacy, Dr. M. G. R Educational and Research Institute, Velappanchavadi, Chennai 600077

Abstract

Objective: In this present study attempt was made to formulate transdermal patches contains phytoconstituents. The naturopathy does not involve any adverse effects.


Methods: Hibiscus rosasinensis aquous extracts was prepared. Transdermalpatches were prepared using drug with two different polymers. The prepared transdermal films were evaluated for their physiochemical characteristics such as physical appearance, weight uniformity, thickness, folding endurance; moisture content, surface pH, Tensile strength. The in-vitro diffusion study was carried out using rat membrane. These parameters indicates the successful release of drug from the fabricated patch.


Results: With the overall observation it was concluded that the.


Conclusion: Fabrication of transdermal patch is successfully worked and subjected to diffusion study. Diffusion studies are carried out by using a fresh rat membrane. Phosphate buffer (6.6) is used as a solvent. Samples are collected for 24 h and absorbance is measured by using UV spectrophotometer at 226 nm. It showed the successful release of drug from the fabricated patch.

Keywords: Hibiscus rosasinensis, Transdermal patch, Comparison

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DHANALAKSHMI, S., N. HARIKRISHNAN, M. DEVI, V. KEERTHANA, and VIJAYALAKSHMI. “FABRICATION AND EVALUATION OF HERBAL TRANSDERMAL FLIM FROM HIBISCUS ROSA SINENSIS”. International Journal of Current Pharmaceutical Research, Vol. 11, no. 5, Sept. 2019, pp. 101-5, doi:10.22159/ijcpr.2019v11i5.35716.
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