IMPACT OF ALCOHOL ON PANCREAS IN ALCOHOLIC PATIENTS

  • FABIHA AIMAN Pharm D Intern, Department of Pharmacy Practice, Care College of Pharmacy, Warangal
  • S. SRIVANI Pharm D Intern, Department of Pharmacy Practice, Care College of Pharmacy, Warangal
  • D. SUDHEER KUMAR Professor, Department of Pharmaceutics, Care College of Pharmacy, Warangal
  • P. KISHORE Pharm D Intern, Department of Pharmacy Practice, Care College of Pharmacy, Warangal

Abstract

Objective: Prolonged hazardous drinking can result in progressive and irreversible damage to the pancreas gland. This occurs on the background of pancreatic inflammation, acinar atrophy and, ultimately, fibrosis and can result in significant exocrine and endocrine insufficiency. Withdrawal of alcohol at an early stage may arrest the process and, even when the condition is established, may reduce the number of inflammatory episodes and allow for better control of both exocrine and endocrine insufficiencies. This study is aimed to identify the impact of alcohol on the pancreas and to educate the patient about the importance of alcohol cessation.


Methods: A retrospective study was conducted in a multispecialty clinic in the gastroenterology department for a period of one month. 60 patients were involved in the study who were diagnosed with pancreatitis (acute or chronic). The data was obtained by directly communicating with the patients which consisted of demographics and social habits.


Results: Among 60 patients, the male was dominant (85%) than female (15%). Majority of the patients were in the age group of 41-60 y (65%) followed by patients 2140 y of age (25%) and patients above 60 y of age (10%). Epigastric pain was the most common presenting complaint in all patients (67%) followed by vomiting (33%). Majority of the patients involved are alcoholics (60%).


Conclusion: Proper attention to the health at the time of diagnosis of disease by alcohol cessation can prevent the progression of the disease and helps the patient to lead a healthy life.

Keywords: Acute pancreatitis, Alcohol, Chronic Pancreatitis

References

1. https://www.mayoclinic.org/diseases-conditions/ pancreatitis/symptoms-causes/syc-20360227. [Last accessed on 05 Oct 2019]
2. Andriy V. Alcohol consumption as a risk factor for acute and chronic pancreatitis: a systematic review and a series of meta-analyses. E Biomed 2015;2:1996–2002.
3. Dulce M. Update on pathogenesis and clinical management of acute pancreatitis. World J Gastrointest Pathophysiol 2012;3:60-70.
4. The National Pancreas Foundation, pancreasfoundation.org/patient-information/chronic-pancreatitis/ [Last accessed on 05 Oct 2019]
5. WR Hasibeder. Critical care of the patient with acute pancreatitis. Anaesth Intensive Care 2009;37:190-206.
6. Marta Herreros Villanueva. Alcohol consumption on pancreatic diseases. World J Gastroenterol 2013;19:638-47.
7. Minoti V, Apte MD. Alcohol-related pancreatic damage. World J Gastroenterol 2013;19:638-47.
8. US Pharm. Acute or chronic inflammation of the endocrine gland. Pancreatitis 2009;34:25-6.
9. Yamandeep Chauhan. A clinical profile and outcome of patients with acute pancreatitis: a prospective study in North India. Arch Int Surgery 2018;8:132-8.
Statistics
19 Views | 18 Downloads
Citatons
How to Cite
AIMAN, F., S. SRIVANI, D. S. KUMAR, and P. KISHORE. “IMPACT OF ALCOHOL ON PANCREAS IN ALCOHOLIC PATIENTS”. International Journal of Current Pharmaceutical Research, Vol. 12, no. 2, Mar. 2020, pp. 11-14, doi:10.22159/ijcpr.2020v12i2.37479.
Section
Original Article(s)