ANTIHYPERGLYCEMIC ACTIVITY OF IMPERATA CYLINDRICA ROOT METHANOL EXTRACT IN RATS
Keywords:Antihyperglycemic, Cogongrass, Glucose absorption, I cylindrical
Objective: This study aims to evaluate the inhibitory activity of Imperatacylindrica root methanol extract on glucose absorption level in intestine of male Wistar strain rats at a dose of 90 mg/kg-bw, which is a dose having antihypertensive activity.
Methods: Extract inhibitory activity on the glucose absorption level in the intestine of the rats followed Soedigdo-Marsongkohadi method. Glucose absorption level was measured from a mixture of 30 mmol glucose in 0.9 % sodium chloride solution as the control solution and a mixture of the extract at the dose of 90 mg/kg-bw in another control solution as the tested solution
Results: The result showed that the extract at the dose of 90 mg/kg-bw had significant activity (p<0.05) to decrease the glucose absorption level in the intestine of the rats.
Conclusion: I. cylindrica root methanol extract at the dose of 90 mg/kg-bw had a significant activity to inhibit the glucose absorption level in the intestine of the rats. Thereby, the extract at the dose of 90 mg/kg-bw had antihyperglycemic activity.
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