PROPHYLACTIC ANTIBIOTICS IN CAESAREAN DELIVERIES IN A TERITIARY CARE TEACHING HOSPITAL

  • RAJASREE GADDE Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • SAJANA GOGINENI Department of Obstetrics and Gynaecology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinoutpalli, Gannavaram, Krishna District, Andhra Pradesh, India
  • KANCHARLA CHANDANA SRI Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • JIRRA INDRAJA Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • MARADANI BRAHMI Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • VIJAYA KUMAR GHANTA Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • VISWA SRUJANI KANAGALA Department of Pharmacy Practice, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India

Abstract

Objective: Prophylactic antibiotics are used to prevent post-operative infections after Caesarean Section. Studies have suggested a significant role in the timing of prophylaxis. The aim of the study was to evaluate the pattern of antibiotics used and to identify the frequency of post-operative infections in patients undergoing Caesarean Section.


Methods: A prospective observational study was carried out for 6 mo. A total of 120 patients who met the inclusion criteria were recruited into the study. Data collection form was prepared using NICE guidelines. A total of 120 medical records were analysed.


Results: The results revealed that out of 120 study subjects, prophylactic antibiotics Cefotaxime, Metronidazole and Cefixime were used in 119 (99.17%).


Conclusion: This study concludes that giving prophylactic antibiotics before skin incision reduces risk of post-operative infections in women undergoing Caesarean Section. As the patients did not produce any infections post-surgery 3rd generation Cephalosporins along with Nitro-imidazoles can be considered as an effective prophylactic therapy for use during caesarean sections.

Keywords: Caesarean section, Prophylactic antibiotics, Pregnant women, Cephalosporins, Nitro-imidazoles, Post-operative infectious complications

References

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GADDE, R., S. GOGINENI, K. C. SRI, J. INDRAJA, M. BRAHMI, V. K. GHANTA, and V. S. KANAGALA. “PROPHYLACTIC ANTIBIOTICS IN CAESAREAN DELIVERIES IN A TERITIARY CARE TEACHING HOSPITAL”. International Journal of Current Pharmaceutical Research, Vol. 13, no. 1, Jan. 2021, pp. 60-63, doi:10.22159/ijcpr.2021v13i1.40817.
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