IDENTIFICATION OF GENES/ ENZYMES RESPONSIBLE FOR ANTIBIOTIC RESISTANCE IN VIBRIO ALGINOLYTICUS STRAIN PTS13


Pingal Kumari, Arun Kumar, S. Thirugnanasambandan Somasundaram

Abstract


Vibrio alginolyticus is a halophilic Gram-negative pathogenic bacterium. It is considered as one of the most frequent species living freely in water and sediment and can survive in sea water even in famine conditions while maintaining their virulence. Gram-negative bacteria are highly efficient in up-regulating or acquiring genes that code for mechanisms of antibiotic resistance, especially in the presence of antibiotic selection pressure. Furthermore, they have available to them a plethora of resistance mechanisms, often using multiple mechanisms against the same antibiotic or using a single mechanism to affect multiple antibiotics. This study began with the observation of multi-resistant Vibrio alginolyticus strain recovered from the coastal sediment of Tuticorin beach. The aim of this study was to determine the prevalence of some important resistance genes encoding bla TEM, bla CTX-M, gyrA and bla VIM in the test isolate i. e. Vibrio alginolyticus strain PTS13.

Keywords: Vibrio alginolyticus, Antibiotic, Resistance, Bla TEM, Bla CTX-M, Gyra, Bla VIM.


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About this article

Title

IDENTIFICATION OF GENES/ ENZYMES RESPONSIBLE FOR ANTIBIOTIC RESISTANCE IN VIBRIO ALGINOLYTICUS STRAIN PTS13

Date

06-01-2015

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Journal

International Journal of Current Pharmaceutical Research
Vol 7, Issue 1, 2015 Page: 76-83

Online ISSN

0975-7066

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Authors & Affiliations

Pingal Kumari
Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai 608502, Tamilnadu, India.

Arun Kumar

S. Thirugnanasambandan Somasundaram


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