MEGALOBLASTIC CRISIS IN SICKLE CELL DISEASE–A RARE PHENOMENA WITH AVAILABLE REVIEW OF LITERATURE

MONICA DASH; PRIYA KUMARI; DIVYA MOHINDRU; PRAGNYA P. MISHRA

doi:10.22159/ijcpr.2024v16i6.5082

Authors

MONICA DASH Department of Pathology, Hitech Medical College, Rourkela, Odisha
PRIYA KUMARI Department of Pathology, Hitech Medical College, Rourkela, Odisha
DIVYA MOHINDRU Department of General medicine, Hitech medical college, Rourkela, Odisha
PRAGNYA P. MISHRA Department of Pathology, Hitech Medical College, Rourkela, Odisha

DOI:

https://doi.org/10.22159/ijcpr.2024v16i6.5082

Keywords:

Crisis, Megaloblastic crisis, Sickle in disease, Vitamin B12, Folic acid, Deficiency

Abstract

Sickle cell disease (SCD) is an inherited disease where some red blood cells are shaped like sickles or crescent moons. This condition affects the blood and various organs of the body. These sickle cells also become rigid and sticky, which can slow or block blood flow, resulting in episodes of sickness that produce pain and other crisis. There are different types of crisis. SCD with a megaloblastic crisis is rare. The frequency of the carrier state determines the prevalence of sickle cell anemia. Here we describe a 20 y old female patient with sickle cell disease who experienced a megaloblastic crisis.

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