A PROSPECTIVE, OBSERVATIONAL DRUG UTILIZATION STUDY IN THE DERMATOLOGY OUT-PATIENT DEPARTMENT OF A GOVERNMENT HOSPITAL, NANDYAL, ANDHRA PRADESH
DOI:
https://doi.org/10.22159/ijcpr.2024v16i6.5087Keywords:
Dermatology, Drug utilization, PolypharmacyAbstract
Objective: The data regarding drug utilization in dermatology departments of southern parts of India is limited. Recent studies on drug utilization in dermatology across India, reported high prescription of branded drugs, low adoption of essential drugs and polypharmacy. Hence, this study was conducted to analyze the drug utilization pattern for common skin diseases as per WHO prescribing indicators.
Methods: This study was done in the Out-patient department (OPD) of dermatology at Government General Hospital (GGH), Nandyal, in collaboration with department of Pharmacology for a period of 4 mo and Institutional ethical committee (IEC) permission was taken before conducting the study.
Results: A total number of 344 prescriptions were analyzed. Average number of drugs per prescription was 2.5 (including Fixed drug combination (FDC) drugs). Total number of drugs accounted to 860. Majority of prescriptions have 3 drugs per prescription (57.1%) and only 8.7% of prescriptions have more than 3 drugs per prescription. Analyzed data as per World Health Organization (WHO) prescribing indicators indicate 74% of prescribed drugs were from National List of Essential Medicines (NLEM), 2.5% were FDC drugs and 13.14% of the drugs prescribed were antibiotics. Polypharmacy was noted to be only 0.7% in the study.
Conclusion: A periodic audit of prescriptions will reduce errors and motivate the health care professionals for rational drug use. Special consideration is to be given to extended public health initiatives to prevent skin infections because they account for about 70% of diseases in daily life.
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References
Hay RJ, Johns NE, Williams HC, Bolliger IW, Dellavalle RP, Margolis DJ. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions. J Invest Dermatol. 2014;134(6):1527-34. doi: 10.1038/jid.2013.446, PMID 24166134.
Gambre R, Khobragade A, Jalikar K, Patel S, Gaidhane S. Analysis of prescribing pattern of drugs among patients attending dermatology outpatient department of a Tertiary Care Hospital. European Journal of Pharmaceutical and Medical Research. 2018;5(3):259-73.
Saravanakumar RT, Prasad GS, Ragul G, Mohanta GP, Manna PK, Moorthi C. Study of prescribing pattern of topical corticosteroids in the department of dermatology in multi-specialty Tertiary Care Teaching Hospital in South India. Int J Res Pharm Sci. 2012;3(4):685-47.
Krishna J, Singh A, Goel S, Roy A, Singh AK, Yadav KP. Clinical pharmacological study of prescribing pattern of dermatological drugs from a Tertiary Care Teaching Hospital. Indian J Sci Res. 20l5;6(2):41-5.
Sjoqvist F, Birkett D. Introduction to drug utilization research (WHO booklet). In: Bramley DW editor. New York: WHO Office of Publication. Drug utilization; 2003. p. 76-9.
Introduction to drug utilization research/WHO International Working Group for Drug Statistics Methodology WHO Collaborating Centre for Drug Statistics Methodology WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services; 2024.
Maini R, Verma KK, Biswas NR, Agrawal SS. Drug utilization study in dermatology in a tertiary hospital in Delhi. Indian J Physiol Pharmacol. 2002;46(1):107-10. PMID 12024948.
Pathak AK, Kumar S, Kumar M, Mohan L, Dikshit H. Study of drug utilization pattern for skin diseases in dermatology OPD of an Indian Tertiary Care Hospital-a prescription survey. J Clin Diagn Res. 2016 Feb;10(2):FC01-5. doi: 10.7860/JCDR/2016/17209.7270, PMCID: PMC4800544.
Vineeta D, Sharad P, Ganachari MS, Geetanjali S, Santosh S. Assessment of drug prescribing pattern and cost analysis for skin disease in dermatological department of Tertiary Care Hospital: an interventional study. J Pharmacovigil. 2016;4(3):211.
Gupta S, Khan W, Krishna A. Pattern of skin diseases and common drugs prescribed in dermatology OPD of an Indian Tertiary Care Hospital. Int J Basic Clin Pharmacol. 2016;6(1):203-7. doi: 10.18203/2319-2003.ijbcp20164780.
Jaiswal MK, Chakrawarty RK, Sharma SK, Sharma RK, Bharti RK, Agrawal R. A World Health Organization core drug use indicator based prescription study in the dermatology outpatient department of a Tertiary Care Teaching Hospital of Central South India. Int J Basic Clin Pharmacol. 2019 Jul;8(8):1896-901. doi: 10.18203/2319-2003.ijbcp20193198.
Sajith M, Lokhande KD, Padma S, Pavvar AP. Prevalence of various skin disorders and prescribing pattern of antihistamines in Tertiary Care Hospital. Pune. Int J Pharm Sci Res. 2014;5(3):73-7.
El Mahalli AA. WHO/INRUD drug prescribing indicators at primary health care centres in Eastern Province Saudi Arabia. East Mediterr Health J. 2012;18(11):1091-6. doi: 10.26719/2012.18.11.1091, PMID 23301369.
Rwevemamu D, Runyoro DK, Temu MJ. Pattern of skin diseases and prescribing practice in dermatology in public and faith-based hospitals in three regions of Tanzania. J Pharm Sci Res. 2017;9(I):55-62.
Gambre R, Khobragade A, Jalikar K, Patel S, Gaidhane S. Analysis of prescribing pattern of drugs among patients attending dermatology outpatient department of a Tertiary Care Hospital. European Journal of Pharmaceutical and Medical Research. 2018;5(3):259-73.
Yuwnate AH, Chandane RD, Giri KR, Yunati M, Sirsam S. A multicentre pharmacoepidemiological study of dermatological disorders in Wardha District. Int J Basic Clin Pharmacol. 2013;2(6):751-6. doi: 10.5455/2319-2003.ijbcp20131215.
Narwane S. Drug utilization and cost analysis for common skin diseases in dermatology OPD of an Indian Tertiary Care Hospital a prescription survey. Br J Pharm Res. 2011;1(1):9-18. doi: 10.9734/BJPR/2011/223.
Chakrawarty R, Jaiswal MK, Sharma S, Sachdev D, Sharma R, Ali SS. Study on prescription pattern of antibiotics in dermatology OPD of a Tertiary Care Teaching Hospital of Tribal Region of India. Int J Biol Med Res. 2017;8(8):491-6. doi: 10.7439/ijbr.v8i8.4351.
Kumar A. Patterns of drug use and drug dispensing in dermatology outpatient prescriptions in a Tertiary Care Teaching Hospital. Int J Basic Clin Pharmacol. 2018;7(8):1494-7. doi: 10.18203/2319-2003.ijbcp20182932.
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