COMPARATIVE ANALYSIS OF EPIDURAL ROPIVACAINE 0.75% VERSUS ROPIVACAINE 0.75% WITH CLONIDINE IN LOWER LIMB SURGERIES: EFFICACY, HEMODYNAMICS, AND SAFETY PROFILE
DOI:
https://doi.org/10.22159/ijcpr.2025v17i1.6027Keywords:
Epidural anesthesia, Ropivacaine, Clonidine, Lower limb surgery, Postoperative pain, Hemodynamic stabilityAbstract
Objective: Epidural ropivacaine is extensively used for lower limb surgeries due to its effective analgesic properties and safety profile. The addition of clonidine as an adjuvant may enhance these effects, but its implications on efficacy, hemodynamics, and safety are not fully established.
Methods: In a double-blind, randomized controlled trial, 80 patients undergoing lower limb surgeries were assigned to receive either ropivacaine 0.75% or ropivacaine 0.75% with clonidine epidurally. Parameters such as onset and duration of sensory and motor blocks, hemodynamic changes, postoperative pain scores, and side effects were meticulously recorded and analyzed.
Results: Clonidine significantly improved the onset and duration of sensory and motor blocks, maintained better hemodynamic stability, and provided superior pain control compared to ropivacaine alone. There were no significant adverse effects requiring intervention beyond standard care.
Conclusion: Clonidine is an effective adjuvant to ropivacaine in epidural anesthesia for lower limb surgeries, enhancing analgesic quality and duration while being hemodynamically stable and safe.
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Copyright (c) 2025 DEVASHISH SINGH SHEKHAWAT, UPENDRA KUMAR, YASH VIJAY
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