A FLEETING DARKNESS: TRANSIENT VISION LOSS IN PSEUDOTUMOR CEREBRI A CASE REPORT

Authors

  • SANJAYKUMAR RATHWA Department of Medicine, Sbks Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0008-9241-8477
  • PRATIKSHA RATHWA Department of Medicine, Sbks Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0007-1746-8303
  • MAULIKKUMAR KARPATIYA Department of Medicine, Sbks Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, India https://orcid.org/0009-0003-0394-4824

DOI:

https://doi.org/10.22159/ijcpr.2025v17i1.6058

Keywords:

Pseudotumor cerebri, Papilledema, High intracranial pressure, Acetazolamide

Abstract

The hallmark of pseudotumor cerebri is a neurological condition marked by high intracranial pressure (ICP) without any discernible localizing signs or neurological impairments with normal intracranial structures. Radiographic exclusion of an intracranial mass is necessary for the mainly clinical diagnosis. We reported a case of a 27-year-old lady presented to the department of general medicine with severe headache and bilateral blurring of vision. Ophthalmoscopy revealed bilateral papilledema. Magnetic resonance imaging (MRI) brain with orbit revealed typical alterations, including bilateral flattening of the posterior sclera and protrusion of the optic nerve heads. Above findings were suggestive of pseudotumor cerebri. Treatment designed to reduce discomfort while preserving vision. Initial treatment included methylprednisolone, mannitol and acetazolamide. Acetazolamide and oral Prednisolone were administered after discharge in a tapering dose over a period of 1 mo.

Downloads

Download data is not yet available.

References

Ball AK, Howman A, Wheatley K, Burdon MA, Matthews T, Jacks AS. A randomised controlled trial of treatment for idiopathic intracranial hypertension. J Neurol. 2011;258(5):874-81. doi: 10.1007/s00415-010-5861-4, PMID 21161260.

Johnston I, Besser M, Morgan MK. Cerebrospinal fluid diversion in the treatment of benign intracranial hypertension. J Neurosurg. 1988;69(2):195-202. doi: 10.3171/jns.1988.69.2.0195, PMID 3392566.

Corbett JJ, Nerad JA, Tse DT, Anderson RL. Results of optic nerve sheath fenestration for pseudotumor cerebri the lateral orbitotomy approach. Arch Ophthalmol. 1988;106(10):1391-7. doi: 10.1001/archopht.1988.01060140555022, PMID 3273487.

Sergott RC, Savino PJ, Bosley TM. Modified optic nerve sheath decompression provides long-term visual improvement for pseudotumor cerebri. Arch Ophthalmol. 1988;106(10):1384-90. doi: 10.1001/archopht.1988.01060140548021, PMID 3178549.

Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology. 2013;81(13):1159-65. doi: 10.1212/WNL.0b013e3182a55f17, PMID 23966248.

Friedman DI, Rausch EA. Headache diagnoses in patients with treated idiopathic intracranial hypertension. Neurology. 2002;58(10):1551-3. doi: 10.1212/wnl.58.10.1551, PMID 12034799.

Radhakrishnan K, Ahlskog JE, Cross SA, Kurland LT, O Fallon WM. Idiopathic intracranial hypertension (pseudotumor cerebri). Descriptive epidemiology in Rochester Minn 1976 to 1990. Arch Neurol. 1993;50(1):78-80. doi: 10.1001/archneur.1993.00540010072020, PMID 8418804.

Giuseffi V, Wall M, Siegel PZ, Rojas PB. Symptoms and disease associations in idiopathic intracranial hypertension (pseudotumor cerebri): a case-control study. Neurology. 1991;41(2_part_1):239-44. doi: 10.1212/WNL.41.2_Part_1.239.

Wall M. The headache profile of idiopathic intracranial hypertension. Cephalalgia. 1990;10(6):331-5. doi: 10.1046/j.1468-2982.1990.1006331.x, PMID 2289234.

Dai Y, Jia N, Wang XL, Chen XH, Sun HL, Zhang XJ. Analysis of characteristics of ocular manifestations of benign intracranial hypertension. Zhonghua Yan Ke Za Zhi. 2010;46(12):1071-4. PMID 21211218.

Thurtell MJ, Wall M. Idiopathic intracranial hypertension (pseudotumor cerebri): recognition treatment and ongoing management. Curr Treat Options Neurol. 2013 Feb;15(1):1-12. doi: 10.1007/s11940-012-0207-4, PMID 23136035.

Thakkar DK, Patil A, Thakkar D, Patil P, Jantre MN. Magnetic resonance imaging in pseudotumor cerebri: a case report. Med J DY Patil Univ. 2014;7(6):802-5. doi: 10.4103/0975-2870.144894.

Published

15-01-2025

How to Cite

RATHWA, S., P. RATHWA, and M. KARPATIYA. “A FLEETING DARKNESS: TRANSIENT VISION LOSS IN PSEUDOTUMOR CEREBRI A CASE REPORT”. International Journal of Current Pharmaceutical Research, vol. 17, no. 1, Jan. 2025, pp. 103-5, doi:10.22159/ijcpr.2025v17i1.6058.

Issue

Section

Case Study(s)