Satish E Bahekar, Ranjana S Kale


Snake bites possess significant amount of mortality as well as morbidity all over the world including India. Despite various species of snakes, only few of these can be potentially lethal to humans. Snake antivenom being only therapeutic option available in snake bite management, but has many drawbacks in actual clinical practice like species specificity, difficulty in availability, affordability and ideal storage conditions. The medicinal plants, available locally and used widely by traditional healers, therefore need attention in this aspects. Large number of plants and their active principles has been evaluated for pharmacological properties useful in the treatment of snake bites. However, numerous unexplored plants are claimed to have definite role in this issue need to be further studied. This review is an attempt to present a comprehensive account of various Indian herbal plants used in the treatment of snake bite in any forms like venom neutralization, topical application for local pain relief, oral formulation for pain relief etc.

Keywords: Herbal plants, Snake bite, Anti-snake venom, Venom neutralisation

| PDF |


Alirol E, Sharma SK, Bawaskar HS, Kuch U, Chappuis F. Snakebite in South Asia: A review. PloS Negl Trop Dis 2010;4:e603.

Bawaskar HS. Snake venoms and antivenom issues: Critical supply issues. J Assoc Physicians India 2004;52:11-3.

Philip E. Snake bite and scorpion sting. In Pediatric and Neonatal Emergency Care. 1994 .Ed. Srivatava, R.N. p 227 - 234.

Gomes A, Bhattacharjee P, Mishra R. Anticancer potential of animal venoms and toxins. Indian J Exp Biol 2010;48:93-103.

Deepika Jain and Sudhir Kumar. Snake Venom: A Potent Anticancer Agent. Asian Pacific J Cancer Prev 2012;13(10):4855-4860.

Bryan G. Fry et al. Effectiveness of Snake Antivenom: Species and Regional Venom Variation and Its Clinical Impact. Journal of Toxicology 2003; 22(1):23-34.

Shashidharamurthy R, Kemparaju K. Region specific neutralization of Indian cobra (Naja naja) venom by polyclonal antibody raised against the eastern regional venom: A comparative study of the venoms from three different geographicaldistributions. Int Immunopharmacol 2007;7:61-9.

Tsai IH, Tsai HY, Wang YM, Tun-Pe, Warrell DA. Venom phospholipases of Russell's vipers from Myanmar and eastern India- cloning,characterization and phylogeographic analysis. Biochim Biophys Acta 2007;1774:1020-8.

C. Algesaboopathi. Medico – botanical survey of plans in Kanjamalai hills of Salem, Tamil Nadu. Ancient Science of Life. 1994;15(1&2): 112-116.

Chandana Choudhury Barua et al. Analgesic and anti-nociceptive activity of hydroethanolic extract of Drymaria cordata Willd. Indian J Pharmacol. 2011;43(2): 121–125.

A Satish, Sudha Sairam, Faiyaz Ahmed, Asna Urooj. Moringa oleifera Lam.: Protease activity against blood coagulation cascade. Pharmacognosy Res. 2012 Jan-Mar; 4(1): 44–49.

Ching-Wen Chang et al. Analgesic and Anti-Inflammatory Activities of Methanol Extract of Cissus repens in Mice. Evid Based Complement Alternat Med. 2012; 2012: 135379.

Barua CC, Talukdar A, Begum SA, Borah P, Lahkar M. Anxiolytic activity of methanol leaf extract of Achyranthes aspera Linn in mice using experimental models of anxiety. Indian J Pharmacol. 2012 Jan;44(1):63-7.

Beg S, Swain S, Hasan H, Barkat M A, Hussain M. Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. Phcog Rev 2011;5:120-37.

Das SN, Patro VJ, Dinda SC. A review: Ethnobotanical survey of genus Leucas. Pharmacogn Rev. 2012 Jul;6(12):100-6.

Bharat K Pradhan, Hemant K Badola. Ethnomedicinal plant use by Lepcha tribe of Dzongu valley, bordering Khangchendzonga Biosphere Reserve, in North Sikkim, India. J Ethnobiol Ethnomed. 2008; 4: 22.

Bhadoriya SS, Ganeshpurkar A, Narwaria J, Rai G, Jain AP. Tamarindus indica : Extent of explored potential. Phcog Rev 2011;5:73-81.

Kumar S, Malhotra R, Kumar D. Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities. Phcog Rev 2010;4:58-61.

Kumar D, Kumar S, Gupta J, Arya R, Gupta A. A review on chemical and biological properties of Cayratia trifolia Linn. (Vitaceae). Phcog Rev 2011;5:184-8.

K. M. Sakthivel , C. Guruvayoorappan. Biophytum sensitivum: Ancient medicine, modern targets. Adv Pharm Technol Res. 2012 Apr-Jun; 3(2): 83–91.

Cheryl Lans. Comparison of plants used for skin and stomach problems in Trinidad and Tobago with Asian ethnomedicine. J Ethnobiol Ethnomed. 2007 Jan 5;3:3.

Gadekar R, Singour P K, Chaurasiya P K, Pawar R S, Patil U K. A potential of some medicinal plants as an antiulcer agents. Phcog Rev 2010;4:136-46.

Grønhaug TE et al. Ethnopharmacological survey of six medicinal plants from Mali, West-Africa. J Ethnobiol Ethnomed. 2008 Dec 27;4:26.

Verma AK, Kumar M, Bussmann RW. Medicinal plants in an urban environment: the medicinal flora of Banares Hindu University, Varanasi, Uttar Pradesh. J Ethnobiol Ethnomed. 2007 Nov 8;3:35.

Panghal M, Arya V, Yadav S, Kumar S, Yadav JP. Indigenous knowledge of medicinal plants used by Saperas community of Khetawas, Jhajjar District, Haryana,India. J Ethnobiol Ethnomed. 2010 Jan 28;6:4.

Belayneh A, Asfaw Z, Demissew S, Bussa NF. Medicinal plants potential and use by pastoral and agro-pastoral communities in Erer Valley of Babile Wereda, Eastern Ethiopia. J Ethnobiol Ethnomed. 2012; 8: 42.

About this article





Additional Links

Manuscript Submission


Innovare Journal of Life Sciences
Vol 1 Issue 1 2013 (Apr-Jun) Page: 19-22

Online ISSN


Authors & Affiliations

Satish E Bahekar
Demonstrator, Dept of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Dist Wardha, Maharashtra 442102

Ranjana S Kale
Professor, Dept of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Dist Wardha, Maharashtra 442102


  • There are currently no refbacks.