ASSESSMENT OF α- AMYLASE INHIBITORY ACTION OF SOME EDIBLE PLANT SOURCES


Jannathul Firdhouse, Lalitha Pottail

Abstract


Diabetes mellitus is one of the major causes for various manifestations of diseases and clinical complications. Plants are good sources of medicinal compounds and some are traditionally used to control Diabetes mellitus. In this study, the anti-diabetic potential of some edible plants was assessed by α-amylase inhibition assay. Among the studied plants, the extracts of Amaranthus dubius and Alternanthera sessilis were found to possess better inhibition potential against α-amylase enzyme. Acarbose and metformin used as standards for reference showed 67% and 48% inhibition efficiency respectively at a concentration of 250 µg/mL and 500 µg/mL. The results of the study ascertain the use of plants in the control of Diabetes mellitus. The inhibitory action of α-amylase mediated through the synergistic action of the phytoconstituents in the plants, lowers the glycemic level, reducing the risks associated with a sudden increase in blood sugar. The results of the study demonstrate the successful use of in vitro models in screening the plant sources for anti-diabetic activity. 


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References


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About this article

Title

ASSESSMENT OF α- AMYLASE INHIBITORY ACTION OF SOME EDIBLE PLANT SOURCES

Date

04-06-2016

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Journal

Innovare Journal of Sciences
VOL 4 ISSUE 3 2016 (JUNE-JULY) Page: 1-7

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2321-5496

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Authors & Affiliations

Jannathul Firdhouse
Avinashilingam University for Women
India

Lalitha Pottail
Assistant Professor (SG) Department of Chemistry Avinashilingam University for Women
India


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