MICROALBUMINURIA â€“ A RISK FACTOR FOR CARDIOVASCULAR DISEASE IN DIABETIC POSTMENOPAUSAL WOMEN
Introduction: Diabetes is one of the common metabolic disorders. Microalbuminuria (MA) is usually estimated in diabetic patients and patients with
risk of renal problems.
Objective: Our aim is to study the occurrence of MA in both apparently normal and diabetic postmenopausal women and to find out the relationship
between MA and cardiovascular risk factors.
Methods: This study was conducted in a tertiary care hospital, Puducherry, for a period of 6 months. Serum and urine samples were taken from 50
apparently normal postmenopausal women and 51 diabetic women and compared. Serum was analyzed for urea, creatinine, uric acid levels, lipid
profile, and the urine sample was estimated for microalbumin, creatinine levels. Urine albumin creatinine ratio and glomerular filtration rate were
calculated using standard methods.
Results: About 47% of diabetic women and 46% of apparently normal postmenopausal women had MA. Total cholesterol (TC), triglycerides (TGL),
and very-low-density lipoprotein (VLDL) values were higher in diabetic women when compared to the normal women. MA positive subjects had
relatively higher TC, low-density lipoprotein, TGL, and VLDL levels when compared to MA negative subjects.
Conclusion: The occurrence of MA in normal postmenopausal women is almost similar to that of diabetic women. This suggests the importance of
screening of MA even in normal postmenopausal women. In addition, abnormal lipid profile in diabetic patients favors the need for regular screening
of MA and lipid profile in all diabetic patients.
Keywords: Microalbuminuria, Diabetes, Postmenopausal women, Lipid profile, Renal parameters.
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