A COMPARATIVE STUDY OF LIPID PROFILE AND ANTIOXIDENTS BETWEEN INDIANS AND IRANIANS IN MYSORE,INDIA

  • Shokoufeh Pourmolaei Biochemistry Department, Tonekabon Branch, Islamic Azad University, P O Box 468461187, Tonekabon, Iran.
  • Zahra Ashkavand
  • Cletus J.M. D’Souza

Abstract

Objective: High Density Lipoprotein (HDL) particles are distinguished by their capacity to exert a wide spectrum of antiatherogenic biological activities, including their ability to protect Low Density Lipoprotein (LDL) against oxidation, and their potent anti-inflammatory actions on cells of the arterial wall. Since now cardiovascular disease ( CVD) is beginning to be recognised as a consequence of inflammation, attention is focussed not only on oxidation but also on inflammation which may be measured as circulating levels of an acute-phase protein, such as C-reactive protein (CRP).

Methods: 5ml of blood was drawn from subjects (Iranians and Indians) in fasting. Lipid profile and lipid per -oxidation and anti-oxidant activities were measured.

Results:  our result showed that the serum lipoproteins of Indians readily get oxidized by Cu++ or benzoyl peroxide. Interestingly, the serum lipoprotein of Iranians living in Mysore also showed a similar profile of Cu++ and Benzoyl peroxide catalysed oxidation.

 Conclusion: Life style and classical risk factors yet higher HDL and higher Paraoxonase (PON) activity in the blood of the Iranians suggests that diet can make a different to the conventional risk factors.

 

Keywords: Lipid profile, CVD, Inflammation, PON,CRP

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How to Cite
Pourmolaei, S., Z. Ashkavand, and D’SouzaC. J. “A COMPARATIVE STUDY OF LIPID PROFILE AND ANTIOXIDENTS BETWEEN INDIANS AND IRANIANS IN MYSORE,INDIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 7, no. 3, July 2014, pp. 72-75, https://innovareacademics.in/journals/index.php/ajpcr/article/view/1148.
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Original Article(s)