A COMPARATIVE STUDY OF LIPID PROFILE AND ANTIOXIDENTS BETWEEN INDIANS AND IRANIANS IN MYSORE,INDIA


Shokoufeh Pourmolaei, Zahra Ashkavand, Cletus J.M. D’Souza

Abstract


Objective: High Density Lipoprotein (HDL) particles are distinguished by their capacity to exert a wide spectrum of antiatherogenic biological activities, including their ability to protect Low Density Lipoprotein (LDL) against oxidation, and their potent anti-inflammatory actions on cells of the arterial wall. Since now cardiovascular disease ( CVD) is beginning to be recognised as a consequence of inflammation, attention is focussed not only on oxidation but also on inflammation which may be measured as circulating levels of an acute-phase protein, such as C-reactive protein (CRP).

Methods: 5ml of blood was drawn from subjects (Iranians and Indians) in fasting. Lipid profile and lipid per -oxidation and anti-oxidant activities were measured.

Results:  our result showed that the serum lipoproteins of Indians readily get oxidized by Cu++ or benzoyl peroxide. Interestingly, the serum lipoprotein of Iranians living in Mysore also showed a similar profile of Cu++ and Benzoyl peroxide catalysed oxidation.

 Conclusion: Life style and classical risk factors yet higher HDL and higher Paraoxonase (PON) activity in the blood of the Iranians suggests that diet can make a different to the conventional risk factors.

 

Keywords: Lipid profile, CVD, Inflammation, PON,CRP


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About this article

Title

A COMPARATIVE STUDY OF LIPID PROFILE AND ANTIOXIDENTS BETWEEN INDIANS AND IRANIANS IN MYSORE,INDIA

Date

01-07-2014

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 7 Issue 3 (July-August) 2014 Page: 72-75

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Shokoufeh Pourmolaei
Biochemistry Department, Tonekabon Branch, Islamic Azad University, P O Box 468461187, Tonekabon, Iran.
Iran, Islamic Republic of

Zahra Ashkavand

Cletus J.M. D’Souza


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