• Sajith Mohandas
  • Sreekumar TR
  • Vishnu Prakash


Objective: The present study was done with the aim to evaluate the anthelmintic activity of Vidangadi churna.

Method: The formulation containing traditionally used herbs viz., Embelia ribes (false black pepper fruit), Hordeum vulgare, Mallotus philippinensis, Terminalia chebula, was tested using adult earthworm Pheritima posthuma against Piperazine citrate (15 mg/ml) and albendazole (20 mg/ml) as standard references and normal saline as control. The time to achieve paralysis of the worms was determined.

Result: Vidangadi churna produced a potent anthelminthic activity against the P. posthuma when compared with reference standards (p < 0.001).

Conclusion: This study shows Vidangadi churna has paralytic effect on Indian earthworms.

Keywords: Vidangadi churna, Pheretima postuma, Piperazine citrate, Albendazole, Anthelminthic activity.

Author Biography

Sreekumar TR


Bundy D A. Immunoepidemiology of intestinal helminthic infection I: The global burden of intestinal nematode disease.Trans Royal Soc Trop Med Hyg 1994; 8: 259-261.

Tagbota S, Townson S. Antiparasitic properties of medicinal and other naturally occurring products, Adv Parasitol 2001; 50:199-205.

Sondhi SM., Shahu R., Magan Archana. Indian Drugs 1994; 31(7): 317-320.

Department of the Army Headquarters .U.S. Army Survival Manual Fm 21-76. Barns

& Noble Inc Encyclopædia Britannica. Encyclopædia Britannica Online. 22 Jan. 2009

Singh D, Swarnkar CP, Khan FA.Anthelminthic resistance in gastrointestinal nematodes in

livestock in India. J Vet Parasit 2002; 16:115-130.

Nadkarni KM. Indian Materia Medica, vol-II, 2ndEdn. Bombay Popular Prakashan, Mumbai,

; 237-239.

Syed Asadulla, Ramandang and Rajasekharan Pharmacognosy Of Embelia Ribes Burm F

International Journal Of Research In Pharmacy And Chemistry 2011, 1(4)

Vidyarthi RD. A Text Book of Zoology. 14thEdn. S.Chand and Co, New Delhi 1977; 322-

Thorn GW, Adams RD, Braunwald E,Issalbacher KJ, Petersdorf RG. Harrison’s Principles of

Internal Medicine. McGraw Hill Co, New York 1977; 1088-1089.

Vigar Z. Atlas of Medical Parasitology. 2nd Edn. PG Publishing House, Singapore, 1984;

- 217.

Nirmal SA, Malwadkar G, Laware RB. Anthelminthic activity of Pongamia glabra

Songlanakarin. J Sci Technol 2007; 29:755-757.

Ravindra GM, Mahajan GS, Mehta AA.Invitro Screening of Cleome viscosa extract

for anthelminthic activity. Pharma Biol 2007;45:766- 768.

Srinivasa U, Venkateshwara Rao J, Krupanidhi AM and Srinivas Y, Anthelmintic activity of

leaves of Clerodendrum Phlomidis, Ind. J. Nat. Prod, 2006, 22(1): 28-30.

Armitage P. Statistical methods in Medical Research. 1st Edn. Blackwell scientific

publication. New York 1971; 217-220.

Garg, L.C. & Mehta, R.K. , In vitro studies on anthelmintic activity of Butea frondosa

and Embelia ribes, J.Vet. Anim. Husb. Res. (India), Vol. 3 (I), PP. 28-31; Biol.Abstr., 1960,

(19), 4630, Abstr., 53776.

Guru, L.V. & Mishra, D.N. Anthelmintic activity of E. ribes (Burm.) in vitro,

Antiseptic, 1964,Vol. 61 (7), 545-550.

Guru, L.V. & Mishra, D.N. Anthelmintic activity of Embelia ribes in vitro, Med. &

Surg. (Baroda), 1965, Vol. 5 (7), 6-10.

Tripathi KD. Essential of Medical Pharmacology. 4th Edn. Jaypee Publication, New Delhi,

; 816-817.



How to Cite

Mohandas, S., S. TR, and V. Prakash. “ANTHELMINTIC ACTIVITY OF VIDANGADI CHURNA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 6, no. 3, July 2013, pp. 94-95,