SCREENING OF ANTIPYRETIC ACTIVITY OF METHANOL EXTRACT OF GRACILARIA CORTICATA J.AG. (RED SEAWEED) IN HARE ISLAND, THOOTHUKUDI, TAMIL NADU, INDIA
Objective: To investigate the antipyretic activity of methanol extract of Gracilaria corticata J.Ag. collected from Hare island, Thoothukudi in the south east coast of Tamil Nadu, India.
Methods: Antipyretic activity was determined by brewer's yeast induced pyrexia method. Dried powder plant materials were subjected to methanol extract at the dose of 200mg/kg and 400mg/kg body weight.
Results: Methanol extract showed potential significant antipyretic activity in both doses (p<0.001 and p<0.01) from 1 hour to 4 hour as compared to the standard drug paracetamol.
Conclusion: The present study has been provided the evidence for the antipyretic activity of Gracilaria corticata J.Ag. which could partly contribute to its ethno medical use.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.