A CASE REPORT ON ROLE OF N-ACETYLCYSTEINE IN NON–ACETAMINOPHEN RELATED ACUTE LIVER INJURY


Anooja Thampi

Abstract


 

Acute liver failure is a clinical entity associated with a high mortality rate and majority of these patients may require liver transplantation. N-Acetylcysteine (NAC), an antioxidant agent that replenishes mitochondrial and cytosolic glutathione stores, is an antidote for acetaminophen poisoning. But their role in non–acetaminophen-related acute liver failure is still not proven. Here, we discuss about a 67 year old male patient diagnosed with hepatitis with acute liver injury who was admitted in Emergency Medicine. He was treated with N- Acetylcysteine infusion for an average of 48 hours and later it was found that his liver function tests improved. In this study, we could find that N-Acetylcysteine plays a major role in improving the liver function test of patients with non–acetaminophen-related acute liver failure.


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References


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About this article

Title

A CASE REPORT ON ROLE OF N-ACETYLCYSTEINE IN NON–ACETAMINOPHEN RELATED ACUTE LIVER INJURY

DOI

10.22159/ajpcr.2016.v9i6.13978

Date

01-11-2016

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 9 Issue 6 November 2016 Page: 7-8

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

233 Views | 263 Downloads

Authors & Affiliations

Anooja Thampi
Amrita viswa vidyapeetam university
India


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