ANTIOXIDANT POTENTIALS AND SIMULTANEOUS ESTIMATION OF QUERCETIN, RUTIN, AND GALLIC ACID IN CURCUMA SPECIES


Sowmya Priya M, Sangilimuthu A, Karpagavalli M, Ramkumar M, Josphin Nirmala A

Abstract


Objective: This study was designed to provide simple and cost-effective methods to quantify the biologically active phenolic compounds such as rutin, quercetin, and gallic acid from Curcuma species and evaluation of the antioxidant potentials of different parts with different solvent extracts of Curcuma species.

Methods: Ultraviolet-visible spectrophotometer was used for the analysis of quercetin, rutin, gallic acid and total flavonoid content of Curcuma species extracts. Antioxidant potentials of Curcuma species extracts were evaluated using 2-2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity.

Results: Ethyl acetate extract of Curcuma aromatica rhizome, aerial part contain higher quantity of quercetin and rutin compared to the other extracts, and also Curcuma species such as Curcuma longa and Curcuma amada contains high antioxidant capacity. The total flavonoid content was high in ethyl acetate extract of Curcuma aromatica as 88.35±0.25 μg/g dry weight of quercetin equivalents.

Conclusion: Different extracts of Curcuma species possess good free radical scavenging activity and the IC50 of Curcuma amada aerial part, Curcuma longa aerial part, and Curcuma aromatica rhizome was 61.65±1.75, 62.95±1.85, and 89.40±0.15 (μg/ml), respectively. The Curcuma species contains high total phenolic compounds and antioxidant potentials.


Keywords


Curcuma aromatica, Curcuma longa, Curcuma amada, Rutin, Quercetin.

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About this article

Title

ANTIOXIDANT POTENTIALS AND SIMULTANEOUS ESTIMATION OF QUERCETIN, RUTIN, AND GALLIC ACID IN CURCUMA SPECIES

Keywords

Curcuma aromatica, Curcuma longa, Curcuma amada, Rutin, Quercetin.

DOI

10.22159/ajpcr.2017.v10i12.14093

Date

01-12-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 12 December 2017 Page: 387-391

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Sowmya Priya M
Department of Biotechnology, Karpagam University, Coimbatore - 641 021, Tamil Nadu, India.
India

Sangilimuthu A
Department of Biotechnology, Karpagam University, Coimbatore - 641 021, Tamil Nadu, India.
India

Karpagavalli M
Department of Pharmaceutical Chemistry, Karpagam College of Pharmacy, Coimbatore - 641032. Tamil Nadu, India.
India

Ramkumar M
Department of Biotechnology, Karpagam University, Coimbatore - 641 021, Tamil Nadu, India.
India

Josphin Nirmala A
Department of Biotechnology, Karpagam University, Coimbatore - 641 021, Tamil Nadu, India.
India


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